799241-79-5Relevant articles and documents
An Efficient Synthesis of a Hydroxyethylamine (HEA) Isostere and Its α-Aminophosphonate and Phosphoramidate Derivatives as Potential Anti-HIV Agents
Bhattacharya, Asish K.,Rana, Kalpeshkumar C.,Pannecouque, Christophe,DeClercq, Eric
, p. 1601 - 1611 (2012/10/29)
HIV protease is a promising drug target for AIDS therapy, and several potent HIV-1 protease inhibitors have been reported to date. Although existing inhibitors exhibit high selectivity, they have also been associated with severe side effects and the possi