3-((di-tert-butylphosphoryl)methyl)-1-mesityl-1H-imidazol-3-ium 4-methylbenzenesulfonate

Base Information

• Chemical Name: 3-((di-tert-butylphosphoryl)methyl)-1-mesityl-1H-imidazol-3-ium 4-methylbenzenesulfonate
• CAS No.: 1416953-42-8
• Molecular Formula: C₇H₇O₃S*C₂₁H₃₄N₂OP
• Molecular Weight: 532.684
• Mol file: 1416953-42-8.mol

Synonyms:3-((di-tert-butylphosphoryl)methyl)-1-mesityl-1H-imidazol-3-ium 4-methylbenzenesulfonate

Chemical Property of 3-((di-tert-butylphosphoryl)methyl)-1-mesityl-1H-imidazol-3-ium 4-methylbenzenesulfonate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-((di-tert-butylphosphoryl)methyl)-1-mesityl-1H-imidazol-3-ium 4-methylbenzenesulfonate

There total 4 articles about 3-((di-tert-butylphosphoryl)methyl)-1-mesityl-1H-imidazol-3-ium 4-methylbenzenesulfonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

di-tert-butyl(tosylmethyl)phosphine oxide + N-(2,4,6-trimethylphenyl)imidazole (25364-44-7) → 3-((di-tert-butylphosphoryl)methyl)-1-mesityl-1H-imidazol-3-ium 4-methylbenzenesulfonate (1416953-42-8)

Guidance literature:

In 1,3,5-trimethyl-benzene; at 170 ℃; Inert atmosphere;

DOI:10.1021/acs.organomet.0c00788

Reference yield: 74.0%

di-tert-butyl(mesitylmethyl)phosphine oxide (1416953-38-2) + N-(2,4,6-trimethylphenyl)imidazole (25364-44-7) → 3-((di-tert-butylphosphoryl)methyl)-1-mesityl-1H-imidazol-3-ium 4-methylbenzenesulfonate (1416953-42-8)

Guidance literature:

In toluene; at 120 ℃; for 168h; Inert atmosphere;

DOI:10.1021/om300487r

Reference yield:

di-tert-butyl(hydroxymethyl)phosphine oxide (131535-19-8) → 3-((di-tert-butylphosphoryl)methyl)-1-mesityl-1H-imidazol-3-ium 4-methylbenzenesulfonate (1416953-42-8)

Guidance literature:

Multi-step reaction with 2 steps

1: triethylamine / tetrahydrofuran / 12 h / 20 °C

2: toluene / 168 h / 120 °C / Inert atmosphere

With triethylamine; In tetrahydrofuran; toluene;

DOI:10.1021/om300487r

upstream raw materials:

di-tert-butyl(hydroxymethyl)phosphine oxide

di-tert-butyl(mesitylmethyl)phosphine oxide

N-(2,4,6-trimethylphenyl)imidazole

p-toluenesulfonyl chloride

Downstream raw materials:

3-mesityl-1-(di-tert-butylphosphinomethyl)imidazol-2-ylidene

3-((di-tert-butylphosphaneyl)methyl)-1-mesityl-1H-imidazol-3-ium chloride