C₂₇H₄₃N₃O₆

Base Information

Chemical Name:C₂₇H₄₃N₃O₆
CAS No.:1357008-05-9
Molecular Formula:C₂₇H₄₃N₃O₆
Molecular Weight:505.655
Hs Code.:

C<sub>27</sub>H<sub>43</sub>N<sub>3</sub>O<sub>6</sub>

Synonyms:C₂₇H₄₃N₃O₆

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Chemical Property of C₂₇H₄₃N₃O₆

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Technology Process of C₂₇H₄₃N₃O₆

There total 10 articles about C₂₇H₄₃N₃O₆ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: Boc-Leu-Phe-MeLeu-OMe

: 1357008-05-9
C₂₇H₄₃N₃O₆

Guidance literature:: Boc-Leu-Phe-MeLeu-OMe; With dihydrogen peroxide; lithium hydroxide; In methanol; at 0 ℃;

With hydrogenchloride; sodium thiosulfate; In methanol; water; pH=1;
DOI:10.1016/j.tet.2011.11.089

Reference yield:

: 13139-15-6,53296-34-7
N-tert-butoxycarbonyl-L-leucine

: 1357008-05-9
C₂₇H₄₃N₃O₆

Guidance literature:: Multi-step reaction with 4 steps

1.1: O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate; N-ethyl-N,N-diisopropylamine / dichloromethane / 1 h / 20 °C / Inert atmosphere

2.1: dihydrogen peroxide; lithium hydroxide / methanol / 0 °C

2.2: pH 1

3.1: O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate; N-ethyl-N,N-diisopropylamine / dichloromethane / 1 h / 20 °C / Inert atmosphere

4.1: dihydrogen peroxide; lithium hydroxide / methanol / 0 °C

4.2: pH 1

With dihydrogen peroxide; O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate; N-ethyl-N,N-diisopropylamine; lithium hydroxide; In methanol; dichloromethane;
DOI:10.1016/j.tet.2011.11.089

Reference yield:

: 1357008-65-1
methyl (S)-2-[(S)-2-(tert-butoxycarbonylamino)-N-methyl-3-phenylpropanamido]-4-methylpentanoate

: 1357008-05-9
C₂₇H₄₃N₃O₆

Guidance literature:: Multi-step reaction with 3 steps

1.1: methoxybenzene; trifluoroacetic acid / dichloromethane / 0.67 h

2.1: O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate; N-ethyl-N,N-diisopropylamine / dichloromethane / 1.5 h / 20 °C / Inert atmosphere

3.1: dihydrogen peroxide; lithium hydroxide / methanol / 0 °C

3.2: pH 1

With dihydrogen peroxide; O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate; methoxybenzene; N-ethyl-N,N-diisopropylamine; trifluoroacetic acid; lithium hydroxide; In methanol; dichloromethane;
DOI:10.1016/j.tet.2011.11.089