Uridine, 5'-O-[(4-methoxyphenyl)diphenylmethyl]-2'-Se-phenyl-2'-seleno-, 3'-methanesulfonate

Base Information

Chemical Name:Uridine, 5'-O-[(4-methoxyphenyl)diphenylmethyl]-2'-Se-phenyl-2'-seleno-, 3'-methanesulfonate
CAS No.:134303-97-2
Molecular Formula:C₃₆H₃₄N₂O₈SSe
Molecular Weight:733.701
Hs Code.:
DSSTox Substance ID:DTXSID601120425

Synonyms:DTXSID601120425;134303-97-2

Suppliers and Price of Uridine, 5'-O-[(4-methoxyphenyl)diphenylmethyl]-2'-Se-phenyl-2'-seleno-, 3'-methanesulfonate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of Uridine, 5'-O-[(4-methoxyphenyl)diphenylmethyl]-2'-Se-phenyl-2'-seleno-, 3'-methanesulfonate

Chemical Property:

Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:8
Rotatable Bond Count:12
Exact Mass:734.12011
Heavy Atom Count:48
Complexity:1200

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:COC1=CC=C(C=C1)C(C2=CC=CC=C2)(C3=CC=CC=C3)OCC4C(C(C(O4)N5C=CC(=O)NC5=O)[Se]C6=CC=CC=C6)OS(=O)(=O)C
Isomeric SMILES:COC1=CC=C(C=C1)C(C2=CC=CC=C2)(C3=CC=CC=C3)OC[C@@H]4[C@H]([C@H]([C@@H](O4)N5C=CC(=O)NC5=O)[Se]C6=CC=CC=C6)OS(=O)(=O)C

Technology Process of Uridine, 5'-O-[(4-methoxyphenyl)diphenylmethyl]-2'-Se-phenyl-2'-seleno-, 3'-methanesulfonate

There total 3 articles about Uridine, 5'-O-[(4-methoxyphenyl)diphenylmethyl]-2'-Se-phenyl-2'-seleno-, 3'-methanesulfonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 133782-81-7
1-[5-O-(4-methoxytrityl)-2-deoxy-2-phenylseleno-β-D-ribofuranosyl]uracil

: 124-63-0
methanesulfonyl chloride

: 134303-97-2
5'-O-MMTr-2'-deoxy-2'-phenylseleno-3'-O-mesyl-uridine

Guidance literature:: With pyridine; at 0 ℃;
DOI:10.1016/S0040-4020(01)86406-1

Reference yield:

: 1666-13-3
diphenyl diselenide

: 134303-97-2
5'-O-MMTr-2'-deoxy-2'-phenylseleno-3'-O-mesyl-uridine

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) LiAlH₄ / 1.) THF, 1h, r.t., 2.) 50 deg. C, overnigth

2: 95 percent / pyridine / 0 °C

With pyridine; lithium aluminium tetrahydride;
DOI:10.1016/S0040-4020(01)86406-1

Reference yield:

: 38642-30-7
2,2'-anhydro-1-[5-O-(4-methoxytrityl)-β-D-arabinofuranosyl]uracil

: 134303-97-2
5'-O-MMTr-2'-deoxy-2'-phenylseleno-3'-O-mesyl-uridine

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) LiAlH₄ / 1.) THF, 1h, r.t., 2.) 50 deg. C, overnigth

2: 95 percent / pyridine / 0 °C

With pyridine; lithium aluminium tetrahydride;
DOI:10.1016/S0040-4020(01)86406-1