Technology Process of (1R,2R)-2-benzyloxymethyl-1-ethanoylcyclopropane
There total 6 articles about (1R,2R)-2-benzyloxymethyl-1-ethanoylcyclopropane which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
dipyridinium dichromate; 5A molecular sieve;
In
dichloromethane;
at 20 ℃;
for 5h;
DOI:10.1021/jo030019v
- Guidance literature:
-
Multi-step reaction with 5 steps
1: NaH / tetrahydrofuran; various solvent(s) / 48 h / 20 °C
2: 737 mg / tetra-n-butylammonium fluoride / tetrahydrofuran / 3 h / 20 °C
3: 88 percent / oxalyl chloride; DMSO; triethylamine / CH2Cl2 / 1.5 h / -78 °C
4: tetrahydrofuran / 5 h / 20 °C
5: 173 mg / PDC; molecular sieves 5 Angstroem / CH2Cl2 / 5 h / 20 °C
With
dipyridinium dichromate; oxalyl dichloride; 5A molecular sieve; tetrabutyl ammonium fluoride; sodium hydride; dimethyl sulfoxide; triethylamine;
In
tetrahydrofuran; dichloromethane;
3: Swern oxidation;
DOI:10.1021/jo030019v
- Guidance literature:
-
Multi-step reaction with 5 steps
1: NaH / tetrahydrofuran; various solvent(s) / 48 h / 20 °C
2: 737 mg / tetra-n-butylammonium fluoride / tetrahydrofuran / 3 h / 20 °C
3: 88 percent / oxalyl chloride; DMSO; triethylamine / CH2Cl2 / 1.5 h / -78 °C
4: tetrahydrofuran / 5 h / 20 °C
5: 173 mg / PDC; molecular sieves 5 Angstroem / CH2Cl2 / 5 h / 20 °C
With
dipyridinium dichromate; oxalyl dichloride; 5A molecular sieve; tetrabutyl ammonium fluoride; sodium hydride; dimethyl sulfoxide; triethylamine;
In
tetrahydrofuran; dichloromethane;
3: Swern oxidation;
DOI:10.1021/jo030019v
