7,10-Dichloro-2-methoxybenzo[b]-1,5-naphthyridine

Base Information

Chemical Name:7,10-Dichloro-2-methoxybenzo[b]-1,5-naphthyridine
CAS No.:6626-40-0
Molecular Formula:C13H8Cl2N2O
Molecular Weight:279.125
Hs Code.:2933990090
European Community (EC) Number:229-588-9
NSC Number:59862
UNII:RF6V2XW3SX
DSSTox Substance ID:DTXSID70216459
Nikkaji Number:J42.019K
Wikidata:Q72466651
Mol file:6626-40-0.mol

Synonyms:6626-40-0;7,10-Dichloro-2-methoxybenzo[b]-1,5-naphthyridine;7,10-dichloro-2-methoxybenzo[b][1,5]naphthyridine;1-Aza-6,9-dichloro-2-methoxyacridine;7,10-Dichloro-2-methoxybenzo(b)-1,5-naphthyridine;EINECS 229-588-9;NSC 59862;RF6V2XW3SX;7,10-Dichloro-2-methoxypyrido(3,2-b)quinoline;BRN 0241112;Pyrido(3,2-b)quinoline, 7,10-dichloro-2-methoxy-;Benzo[b]-1,5-naphthyridine, 7,10-dichloro-2-methoxy-;NSC-59862;BENZO(b)-1,5-NAPHTHYRIDINE, 7,10-DICHLORO-2-METHOXY-;4-23-00-02772 (Beilstein Handbook Reference);7,10-Dichloro-2-methoxypyrido[3,2-b]quinoline;7,2-b]quinoline;7,5-naphthyridine;NSC59862;UNII-RF6V2XW3SX;NCIOpen2_002424;SCHEMBL6723708;DTXSID70216459;BCP27022;MFCD00160720;AKOS015900247;Pyrido[3, 7,10-dichloro-2-methoxy-;7,10-dichloro-2-methoxybenzo[b][1,5];AS-44337;LS-38611;WLN: T C666 BN GNJ FO1 IG MG;Benzo[b]-1, 7,10-dichloro-2-methoxy-;CS-0150209;FT-0648045;A15741;7,10-dichloro-2-methoxypyrido [3,2-b]quinoline;J-519054

Suppliers and Price of 7,10-Dichloro-2-methoxybenzo[b]-1,5-naphthyridine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
7,10-Dichloro-2-methoxybenzo[b][1,5]naphthyridine
5 g
$ 495.00

TRC
7,10-Dichloro-2-methoxybenzo[b][1,5]naphthyridine
500mg
$ 110.00

Matrix Scientific
7,10-Dichloro-2-methoxybenzo[b]-1,5-naphthyridine 95+%
1g
$ 258.00

Matrix Scientific
7,10-Dichloro-2-methoxybenzo[b]-1,5-naphthyridine 95+%
5g
$ 515.00

Labseeker
7,10-dichloro-2-methoxybenzo[b][1,5]naphthyridine 95
50g
$ 833.00

Crysdot
7,10-Dichloro-2-methoxybenzo[b]-1,5-naphthyridine 95+%
5g
$ 773.00

Crysdot
7,10-Dichloro-2-methoxybenzo[b]-1,5-naphthyridine 95+%
1g
$ 387.00

Biosynth Carbosynth
7,10-Dichloro-2-methoxybenzo(b)-1,5-naphthyridine
10 mg
$ 203.00

Biosynth Carbosynth
7,10-Dichloro-2-methoxybenzo(b)-1,5-naphthyridine
2 mg
$ 59.00

Biosynth Carbosynth
7,10-Dichloro-2-methoxybenzo(b)-1,5-naphthyridine
25 mg
$ 405.00

Total 34 raw suppliers

Chemical Property of 7,10-Dichloro-2-methoxybenzo[b]-1,5-naphthyridine

Chemical Property:

Vapor Pressure:2.48E-07mmHg at 25°C
Melting Point:186-187 °C
Refractive Index:1.704
Boiling Point:434 °C at 760 mmHg
PKA:0.49±0.40(Predicted)
Flash Point:216.3 °C
PSA：35.01000
Density:1.453 g/cm³
LogP:4.09840
Storage Temp.:under inert gas (nitrogen or Argon) at 2-8°C
Solubility.:Chloroform (Sparingly), DMSO (Slightly, Heated), Methanol (Slightly, Heated)
XLogP3:4.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:278.0013683
Heavy Atom Count:18
Complexity:305

Purity/Quality:

99%, ^*data from raw suppliers

7,10-Dichloro-2-methoxybenzo[b][1,5]naphthyridine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Canonical SMILES:COC1=NC2=C(C3=C(C=C(C=C3)Cl)N=C2C=C1)Cl
Uses 7,10-Dichloro-2-methoxybenzo[b][1,5]naphthyridine is used in the preparation of pyronaridine.

Technology Process of 7,10-Dichloro-2-methoxybenzo[b]-1,5-naphthyridine

There total 12 articles about 7,10-Dichloro-2-methoxybenzo[b]-1,5-naphthyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 6626-07-9
4-chloro-2-(6-methoxy-pyridin-3-yl-amino)-benzoic acid

: 6626-40-0
2-methoxy-7,10-dichloropyrido<3,2-b>quinoline

Guidance literature:: With trichlorophosphate; In 1,4-dioxane; at 120 ℃; Cooling with ice; Inert atmosphere;

Reference yield: 95.0%

: 4-chloro-2-(6-methoxypyridin-3-ylamino)benzoic acid hydrochloride

: 6626-40-0
2-methoxy-7,10-dichloropyrido<3,2-b>quinoline

Guidance literature:: With triethylamine; trichlorophosphate; In toluene; at 8 ℃; for 4h; Time; Solvent; Temperature; Inert atmosphere; Reflux; Large scale;
DOI:10.1021/op400357f