(S)-(-)-2--5-hydroxytetralin

Base Information

Chemical Name:(S)-(-)-2--5-hydroxytetralin
CAS No.:129388-80-3
Molecular Formula:C₂₁H₂₈N₂O
Molecular Weight:324.466
Hs Code.:

(S)-(-)-2-<N-(p-aminophenethyl)amino>-5-hydroxytetralin

Synonyms:(S)-(-)-2--5-hydroxytetralin

Suppliers and Price of (S)-(-)-2--5-hydroxytetralin

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (S)-(-)-2--5-hydroxytetralin

Chemical Property:

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Technology Process of (S)-(-)-2--5-hydroxytetralin

There total 7 articles about (S)-(-)-2--5-hydroxytetralin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: [2-(4-Amino-phenyl)-ethyl]-((S)-5-methoxy-1,2,3,4-tetrahydro-naphthalen-2-yl)-propyl-amine

: 129388-80-3
(S)-(-)-2--5-hydroxytetralin

Guidance literature:: With boron tribromide; In dichloromethane; at -78 ℃;
DOI:10.1021/jm00115a012

Reference yield:

: 32940-15-1
5-methoxy-2-tetralone

: 129388-80-3
(S)-(-)-2--5-hydroxytetralin

Guidance literature:: Multi-step reaction with 7 steps

1: 1.) p-TsOH, 2.) H₂ / 2.) PtO₂ / 1.) toluene, reflux, 2 h, 2.) EtOH, 32 psi, 1 h

4: 5percent aq. NaOH / CH₂Cl₂ / 0.17 h / 25 °C

5: BH₃ / tetrahydrofuran / 2 h / Heating

6: hydrazine hydrate, Raney Ni / ethanol / 50 °C

7: BBr₃ / CH₂Cl₂ / -78 °C

With sodium hydroxide; borane; hydrogen; boron tribromide; nickel; toluene-4-sulfonic acid; hydrazine hydrate; platinum(IV) oxide; In tetrahydrofuran; ethanol; dichloromethane;
DOI:10.1021/jm00115a012

Reference yield:

: 136247-07-9
2-(N-benzylamino)-5-methoxytetralin

: 129388-80-3
(S)-(-)-2--5-hydroxytetralin

Guidance literature:: Multi-step reaction with 6 steps

3: 5percent aq. NaOH / CH₂Cl₂ / 0.17 h / 25 °C

4: BH₃ / tetrahydrofuran / 2 h / Heating

5: hydrazine hydrate, Raney Ni / ethanol / 50 °C

6: BBr₃ / CH₂Cl₂ / -78 °C

With sodium hydroxide; borane; boron tribromide; nickel; hydrazine hydrate; In tetrahydrofuran; ethanol; dichloromethane;
DOI:10.1021/jm00115a012