32940-15-1

Basic information

• Product Name: 5-Methoxy-2-tetralone
• Synonyms: 2(1H)-NAPHTHALENONE, 3,4-DIHYDRO-5-METHOXY-;5-METHOXY-3,4-DIHYDRO-1H-NAPHTHALEN-2-ONE;5-METHOXY-2-TETRALONE;5M2T;5-METHOXY-3,4-DIHYDRONAPHTHALEN-2(1H)-ONE;5-Methoxyl-2-Tetralone;Methoxy-2-tetralone,5-;5-Methoxy-3,4-dihydronaphthalen-2(1H)-one 97%
• CAS NO: 32940-15-1
• Molecular Formula: C₁₁H₁₂O₂
• Molecular Weight: 176.21
• Product Categories: Naphthalene derivatives;Fused Ring Systems;C11 to C12;Carbonyl Compounds;Ketones;Aromatics;Intermediates & Fine Chemicals;Pharmaceuticals
• Mol File: 32940-15-1.mol
• Article Data: 19

Chemical Properties

• Melting Point: 32-36 °C(lit.)
• Boiling Point: 165°C/10mmHg(lit.)
• Flash Point: >230 °F
• Appearance: /
• Density: 1.124 g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.549
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature
• Solubility: Chloroform, Dichloromethane, Ethyl Acetate, Methanol
• BRN: 1451623
• CAS DataBase Reference: 5-Methoxy-2-tetralone(CAS DataBase Reference)
• NIST Chemistry Reference: 5-Methoxy-2-tetralone(32940-15-1)
• EPA Substance Registry System: 5-Methoxy-2-tetralone(32940-15-1)

Safety Data

• Hazard Codes: Xn
• Statements: 20/21/22-36/37/38
• Safety Statements: 26-36-24/25
• WGK Germany: 3
• Hazardous Substances Data: 32940-15-1(Hazardous Substances Data)

Usage

Chemical Properties

Orange Solid

Uses

Intermediate in the production of Rotigotine

InChI:InChI=1/C11H12O2/c1-13-11-4-2-3-8-7-9(12)5-6-10(8)11/h2-4H,5-7H2,1H3

Upstream product

• 32940-13-9 1,4-dihydro-2,5-dimethoxynaphthalene 
• 1160858-14-9 C₁₃H₁₆O₅ 
• 1190847-91-6 C₁₅H₂₄O₄ 
• 74-85-1 ethene 
• 6834-42-0 3-methoxyphenylacetic acid chloride 
• 33892-75-0 5-Methoxy-1-tetralone 
• 60573-59-3 8-Methoxy-1,2-dihydronaphthalene 
• 28033-63-8 2-(2-methoxyphenyl)acetyl chloride 
• 135-02-4 ortho-anisaldehyde 
• 90-02-8 salicylaldehyde 
• 121985-99-7 2-hydroxy-2-(2-methoxyphenyl)acetonitrile 
• 124067-29-4 3-(2-anisyl)-α-diazo-2-propanone 
• 1011-54-7 2-methoxycinnamic acid 
• 93-25-4 2-methoxyphenylacetic acid 

Downstream Products

• 87056-67-5 1,2,3,4-tetrahydro-5-methoxy-2-oxo-1,1-bis(phenylthio)naphthalene 
• 87732-53-4 (S)-1-(3,4-Dihydro-5-methoxy-2-naphthyl)-2-(methoxymethyl)pyrrolidin 
• 4018-91-1 2-Amino-5-methoxy-1,2,3,4-tetrahydronaphthalene 
• 101403-25-2 (R)-1,2,3,4-tetrahydro-5-methoxy-N-propyl-naphthalen-2-amine 
• 101403-24-1 (S)-(5-methoxy-1,2,3,4-tetrahydro-naphthalen-2-yl)-propylamine hydrochloride 
• 183542-77-0 5-Methoxy-N-(4-(4-phenylbenzoylamino)butyl)-2-(R,S)-propylamino-1,2,3,4-tetrahydronaphthalene 
• 183542-92-9 5-hydroxy-N-(4-(4-phenylbenzoylamino)butyl)-2-(R,S)-propylamino-1,2,3,4-tetrahydronaphthalene 
• 183542-73-6 5-methoxy-N-(4-(4-phenylbenzoylamino)butyl)-2-(R,S)-methyl-amino-1,2,3,4-tetrahydronaphthalene 
• 78598-91-1 2-(N-propylamino)-5-methoxytetraline 
• 1026500-90-2 1-benzyl-6-methoxy-3,4,4a,5-tetrahydro-1H-benzo[g]quinolin-2-one 
• 1028273-75-7 1-benzyl-6-methoxy-1,2,3,4,4a,5-hexahydro-benzo[g]quinoline 
• 114916-49-3 cis-1-benzyl-6-methoxy-1,2,3,4,4a,5,10,10a-octahydrobenzoquinoline 

Relevant articles and documents

An unexpected double-bond isomerization catalyzed by Crabtree's iridium(I) catalyst

The first iridium-catalyzed isomerization of an exocyclic into an endocyclic double bond is described. A mechanism is proposed for this reaction. Crabtree's catalyst thus allows the migration of a double bond that does not occur under classical conditions. Georg Thieme Verlag Stuttgart.

Synthesis method of 5-methoxy-2-tetralone

The invention discloses a synthesis method of 5-methoxy-2-tetralone, the synthesis method comprises the following steps: reacting 3-methoxyphenylacetic acid with thionyl chloride in the presence of a catalyst solvent to obtain a reaction product containin

Anti-Markovnikov Oxidation of β-Alkyl Styrenes with H2O as the Terminal Oxidant

Oxygenation of alkenes is one of the most straightforward routes for the construction of carbonyl compounds. Wacker oxidation provides a broadly useful strategy to convert the mineral oil into higher value-added carbonyl chemicals. However, the conventional Wacker chemistry remains problematic, such as the poor activity for internal alkenes, the lack of anti-Markovnikov regioselectivity, and the high cost and chemical waste resulted from noble metal catalysts and stoichiometric oxidant. Here, we describe an unprecedented dehydrogenative oxygenation of β-alkyl styrenes and their derivatives with water under external-oxidant-free conditions by utilizing the synergistic effect of photocatalysis and proton-reduction catalysis that can address these challenges. This dual catalytic system possesses the single anti-Markovnikov selectivity due to the property of the visible-light-induced alkene radical cation intermediate.

TiCl4-promoted intramolecular cyclization of 4-methoxy-5-arylethyl-1,3-dioxolan-2-ones: an expedient method to prepare 2-tetralones

DABCO is a very effective catalyst in the formation of 4-methoxy-5-arylethyl-1,3-dioxolan-2-ones 12 from the corresponding α-carbonatoaldehyde. Intramolecular cyclization of cyclic carbonates 12 promoted by TiCl4 affords 2-tetralones 13 contain