C₃₉H₅₈N₄O₄

Base Information

• Chemical Name: C₃₉H₅₈N₄O₄
• CAS No.: 1374310-68-5
• Molecular Formula: C₃₉H₅₈N₄O₄
• Molecular Weight: 646.914
• Mol file: 1374310-68-5.mol

Synonyms:C₃₉H₅₈N₄O₄

Chemical Property of C₃₉H₅₈N₄O₄

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₃₉H₅₈N₄O₄

There total 11 articles about C₃₉H₅₈N₄O₄ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

palmitic anhydride (623-65-4) + TGX-D1 (1308384-65-7) → C39H58N4O4 (1374310-68-5)

Guidance literature:

With pyridine; In dichloromethane; at 0 - 22 ℃;

DOI:10.1021/mp3000309

Reference yield:

3-bromo-5-methylpyridin-2-amine (17282-00-7) → C39H58N4O4 (1374310-68-5)

Guidance literature:

Multi-step reaction with 9 steps

1: dichloromethane / 48 h / 22 °C

2: triethylamine / dichloromethane / 1 h / 22 °C

3: dichloromethane / 24 h / Reflux

4: palladium bis[bis(diphenylphosphino)ferrocene] dichloride; N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide / 16.5 h / 22 - 120 °C / Inert atmosphere

5: hydrogenchloride; water / N,N-dimethyl-formamide / 22 °C

6: sodium tetrahydroborate / methanol; dichloromethane / 0 - 22 °C

7: triethylamine / dichloromethane / 0 - 22 °C

8: triethylamine / dichloromethane / 15 h / Reflux

9: pyridine / dichloromethane / 0 - 22 °C

With pyridine; hydrogenchloride; sodium tetrahydroborate; palladium bis[bis(diphenylphosphino)ferrocene] dichloride; water; triethylamine; N-ethyl-N,N-diisopropylamine; In methanol; dichloromethane; N,N-dimethyl-formamide;

DOI:10.1021/mp3000309

Reference yield:

aniline (62-53-3) → C39H58N4O4 (1374310-68-5)

Guidance literature:

Multi-step reaction with 3 steps

1: 4 h / 90 °C / Inert atmosphere

2: triethylamine / dichloromethane / 15 h / Reflux

3: pyridine / dichloromethane / 0 - 22 °C

With pyridine; triethylamine; In dichloromethane;

DOI:10.1021/mp3000309

upstream raw materials:

palmitic anhydride

TGX-D₁

9-(1-hydroxyethyl)-7-methyl-2-morpholino-4H-pyrido[1,2-a]pyrimidin-4-one

C₁₆H₂₁N₃O₅S