2-(4-benzyloxy-2,6-dichloro-benzyl)-2-(2-oxo-ethyl)-malonicacid diethyl ester

Base Information

Chemical Name:2-(4-benzyloxy-2,6-dichloro-benzyl)-2-(2-oxo-ethyl)-malonicacid diethyl ester
CAS No.:955373-58-7
Molecular Formula:C₂₃H₂₄Cl₂O₆
Molecular Weight:467.346
Hs Code.:

Synonyms:2-(4-benzyloxy-2,6-dichloro-benzyl)-2-(2-oxo-ethyl)-malonicacid diethyl ester

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Chemical Property of 2-(4-benzyloxy-2,6-dichloro-benzyl)-2-(2-oxo-ethyl)-malonicacid diethyl ester

Chemical Property:

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Technology Process of 2-(4-benzyloxy-2,6-dichloro-benzyl)-2-(2-oxo-ethyl)-malonicacid diethyl ester

There total 2 articles about 2-(4-benzyloxy-2,6-dichloro-benzyl)-2-(2-oxo-ethyl)-malonicacid diethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 955373-57-6
2-(4-benzyloxy-2,6-dichloro-benzyl)-2-(2,2-dimethoxy-ethyl)-malonic acid diethyl ester

: 955373-58-7
2-(4-benzyloxy-2,6-dichloro-benzyl)-2-(2-oxo-ethyl)-malonicacid diethyl ester

Guidance literature:: With formic acid; In acetone; for 24h;

Reference yield:

: 886616-14-4
5-benzyloxy-2-bromomethyl-1,3-dichloro-benzene

: 955373-58-7
2-(4-benzyloxy-2,6-dichloro-benzyl)-2-(2-oxo-ethyl)-malonicacid diethyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: lithium hexamethyldisilazane / tetrahydrofuran / 0.25 h / -78 °C

2: formic acid / acetone / 24 h

With formic acid; lithium hexamethyldisilazane; In tetrahydrofuran; acetone;