C₂₄H₂₉N₅O₄

Base Information

• Chemical Name: C₂₄H₂₉N₅O₄
• CAS No.: 1373496-82-2
• Molecular Formula: C₂₄H₂₉N₅O₄
• Molecular Weight: 451.525
• Mol file: 1373496-82-2.mol

Synonyms:C₂₄H₂₉N₅O₄

Chemical Property of C₂₄H₂₉N₅O₄

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₄H₂₉N₅O₄

There total 7 articles about C₂₄H₂₉N₅O₄ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

C10H12N4O2 (1373496-76-4) + C14H17NO2 (1373496-75-3) → C24H29N5O4 (1373496-82-2)

Guidance literature:

With copper(ll) sulfate pentahydrate; sodium L-ascorbate; tris[(1-benzyl-1H-1,2,3-triazol-4yl)methyl]amine; In tetrahydrofuran; methanol; water; at 20 ℃; for 12h; Inert atmosphere;

DOI:10.1021/jo300063u

Reference yield:

2-amino-phenol (95-55-6) → C24H29N5O4 (1373496-82-2)

Guidance literature:

Multi-step reaction with 5 steps

1.1: hydrogenchloride; sodium nitrite / water / 0.08 h / -5 - -3 °C / Inert atmosphere

1.2: Inert atmosphere

1.3: 2 h / 0 °C / Inert atmosphere

2.1: potassium carbonate; potassium iodide / N,N-dimethyl-formamide / 12 h / 20 °C / Inert atmosphere

3.1: lithium hydroxide monohydrate / tetrahydrofuran; water / 12 h / 20 °C / Inert atmosphere

3.2: pH 4

4.1: dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine / dichloromethane / 24 h / -5 - 20 °C / Inert atmosphere

5.1: copper(ll) sulfate pentahydrate; sodium L-ascorbate; tris[(1-benzyl-1H-1,2,3-triazol-4yl)methyl]amine / tetrahydrofuran; methanol; water / 12 h / 20 °C / Inert atmosphere

With hydrogenchloride; dmap; copper(ll) sulfate pentahydrate; lithium hydroxide monohydrate; potassium carbonate; sodium L-ascorbate; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine; potassium iodide; sodium nitrite; tris[(1-benzyl-1H-1,2,3-triazol-4yl)methyl]amine; In tetrahydrofuran; methanol; dichloromethane; water; N,N-dimethyl-formamide;

DOI:10.1021/jo300063u

Reference yield:

C8H7N3O3 (1373496-72-0) → C24H29N5O4 (1373496-82-2)

Guidance literature:

Multi-step reaction with 2 steps

1: dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine / dichloromethane / 24 h / -5 - 20 °C / Inert atmosphere

2: copper(ll) sulfate pentahydrate; sodium L-ascorbate; tris[(1-benzyl-1H-1,2,3-triazol-4yl)methyl]amine / tetrahydrofuran; methanol; water / 12 h / 20 °C / Inert atmosphere

With dmap; copper(ll) sulfate pentahydrate; sodium L-ascorbate; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine; tris[(1-benzyl-1H-1,2,3-triazol-4yl)methyl]amine; In tetrahydrofuran; methanol; dichloromethane; water;

DOI:10.1021/jo300063u

upstream raw materials:

C₈H₇N₃O₃

C₁₁H₁₀O₃

C₁₀H₁₂N₄O₂

C₁₄H₁₇NO₂