6-Benzyloxy-4-methoxymethyl-beta-carboline-3-carboxylic acid ethyl ester

Base Information

Chemical Name:6-Benzyloxy-4-methoxymethyl-beta-carboline-3-carboxylic acid ethyl ester
CAS No.:83910-44-5
Molecular Formula:C23H22 N2 O4
Molecular Weight:390.439
Hs Code.:2933990090
UNII:B6PWX5B47Q
DSSTox Substance ID:DTXSID101004052
Nikkaji Number:J23.674H
Wikipedia:ZK-93423
Wikidata:Q8063121
Pharos Ligand ID:PK7J5B7C26XQ
ChEMBL ID:CHEMBL1518572
Mol file:83910-44-5.mol

Synonyms:6-benzyloxy-4-methoxymethyl-beta-carboline-3-carboxylic acid ethyl ester;ZK 93 423;ZK 93423;ZK-93423

Suppliers and Price of 6-Benzyloxy-4-methoxymethyl-beta-carboline-3-carboxylic acid ethyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
ZK 93423 hydrochloride
10mg
$ 466.00

TRC
Ethyl6-Benzyloxy-4-methoxymethyl-?-carboline-3-carboxylate
10mg
$ 165.00

TRC
Ethyl6-Benzyloxy-4-methoxymethyl-?-carboline-3-carboxylate
100mg
$ 1320.00

American Custom Chemicals Corporation
ZK-93423 95.00%
5MG
$ 503.78

Total 6 raw suppliers

Chemical Property of 6-Benzyloxy-4-methoxymethyl-beta-carboline-3-carboxylic acid ethyl ester

Chemical Property:

Vapor Pressure:2.97E-15mmHg at 25°C
Boiling Point:619.1°C at 760 mmHg
Flash Point:328.2°C
PSA：73.44000
Density:1.269g/cm³
LogP:4.61820
Storage Temp.:Desiccate at RT
XLogP3:4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:8
Exact Mass:390.15795719
Heavy Atom Count:29
Complexity:539

Purity/Quality:

98%Min ^*data from raw suppliers

ZK 93423 hydrochloride ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)C1=NC=C2C(=C1COC)C3=C(N2)C=CC(=C3)OCC4=CC=CC=C4
Uses Ethyl 6-Benzyloxy-4-methoxymethyl-?-carboline-3-carboxylate is a derivative of DMCM (D494120). DMCM is a member of a family of non-benzodiazepine GABAA receptor agonists.

Technology Process of 6-Benzyloxy-4-methoxymethyl-beta-carboline-3-carboxylic acid ethyl ester

There total 11 articles about 6-Benzyloxy-4-methoxymethyl-beta-carboline-3-carboxylic acid ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: ethyl 6-benzyloxy-4,9-bis(methoxymethyl)-9H-pyrido[3,4-b]indole-3-carboxylate

: 83910-44-5
3-carboethoxy-4-methoxymethyl-6-benzyloxy-β-carboline

Guidance literature:: With hydrogenchloride; In ethanol; at 70 ℃; for 24h;
DOI:10.1021/jo026317u

Reference yield:

: 1215-59-4
5-benzyloxy-1H-indole

: 83910-44-5
3-carboethoxy-4-methoxymethyl-6-benzyloxy-β-carboline

Guidance literature:: Multi-step reaction with 3 steps

1.1: acetic acid / toluene / 4 h / Heating

2.1: 8.1 g / hydrogen / Raney nickel / ethanol / 6 h / 1900 Torr

3.1: ethyl acetate; H₂O / 20 °C

3.2: Pd/C / xylene / Heating

With hydrogen; acetic acid; nickel; In ethanol; water; ethyl acetate; toluene; 1.1: Substitution / 2.1: Catalytic hydrogenation / 3.1: Condensation / 3.2: Dehydrogenation;

Reference yield:

: 210160-48-8
3-[5-(benzyloxy)indole-3-yl]-4-methoxy-2-nitrobutanoic acid ethyl ester

: 83910-44-5
3-carboethoxy-4-methoxymethyl-6-benzyloxy-β-carboline

Guidance literature:: Multi-step reaction with 2 steps

1.1: 8.1 g / hydrogen / Raney nickel / ethanol / 6 h / 1900 Torr

2.1: ethyl acetate; H₂O / 20 °C

2.2: Pd/C / xylene / Heating

With hydrogen; nickel; In ethanol; water; ethyl acetate; 1.1: Catalytic hydrogenation / 2.1: Condensation / 2.2: Dehydrogenation;