ethyl 1-(1-benzyl-2,5-dioxopyrrolidin-3-yl)-2-oxocyclopentane-1-carboxylate

Base Information

• Chemical Name: ethyl 1-(1-benzyl-2,5-dioxopyrrolidin-3-yl)-2-oxocyclopentane-1-carboxylate
• CAS No.: 1263036-74-3
• Molecular Formula: C₁₉H₂₁NO₅
• Molecular Weight: 343.379

Synonyms:ethyl 1-(1-benzyl-2,5-dioxopyrrolidin-3-yl)-2-oxocyclopentane-1-carboxylate

Chemical Property of ethyl 1-(1-benzyl-2,5-dioxopyrrolidin-3-yl)-2-oxocyclopentane-1-carboxylate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of ethyl 1-(1-benzyl-2,5-dioxopyrrolidin-3-yl)-2-oxocyclopentane-1-carboxylate

There total 3 articles about ethyl 1-(1-benzyl-2,5-dioxopyrrolidin-3-yl)-2-oxocyclopentane-1-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-benzyl-1H-pyrrole-2,5-dione (1631-26-1) + 2-ethoxycarbonyl-1-cyclopentanone (611-10-9) → ethyl 1-(1-benzyl-2,5-dioxopyrrolidin-3-yl)-2-oxocyclopentane-1-carboxylate (1263036-74-3) + ethyl 1-(1-benzyl-2,5-dioxopyrrolidin-3-yl)-2-oxocyclopentane-1-carboxylate (1263036-73-2) + ethyl 1-(1-benzyl-2,5-dioxopyrrolidin-3-yl)-2-oxocyclopentane-1-carboxylate (1186318-46-6)

Guidance literature:

With cinchonine; In toluene; at 20 ℃; for 96h; Solvent; Reagent/catalyst; Time; Overall yield = 89 %; Optical yield = 48 %de; enantioselective reaction;

DOI:10.1007/s10562-012-0915-0

Reference yield:

1-benzyl-1H-pyrrole-2,5-dione (1631-26-1) + 2-ethoxycarbonyl-1-cyclopentanone (611-10-9) → ethyl 1-(1-benzyl-2,5-dioxopyrrolidin-3-yl)-2-oxocyclopentane-1-carboxylate (1263036-74-3) + ethyl 1-(1-benzyl-2,5-dioxopyrrolidin-3-yl)-2-oxocyclopentane-1-carboxylate (1186318-46-6)

Guidance literature:

With quinine functionalized Fe₃O₄*SiO₂ nanoparticles (MNPs-QN); In toluene; at 0 ℃; for 48h; Overall yield = 86 %; stereoselective reaction; Inert atmosphere;

DOI:10.1016/j.cclet.2017.06.022

Reference yield:

1-benzyl-1H-pyrrole-2,5-dione (1631-26-1) + 2-ethoxycarbonyl-1-cyclopentanone (611-10-9) → ethyl 1-(1-benzyl-2,5-dioxopyrrolidin-3-yl)-2-oxocyclopentane-1-carboxylate (1263036-74-3) + ethyl 1-(1-benzyl-2,5-dioxopyrrolidin-3-yl)-2-oxocyclopentane-1-carboxylate (1263036-73-2) + ethyl 1-(1-benzyl-2,5-dioxopyrrolidin-3-yl)-2-oxocyclopentanecarboxylate (1408475-42-2)

Guidance literature:

With triethylamine; In toluene; at 20 ℃; for 144h; optical yield given as %ee; diastereoselective reaction;

DOI:10.1007/s10562-010-0509-7

upstream raw materials:

1-benzyl-1H-pyrrole-2,5-dione

2-ethoxycarbonyl-1-cyclopentanone

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 1263036-74-3 ethyl 1-(1-benzyl-2,5-dioxopyrrolidin-3-yl)-2-oxocyclopentane-1-carboxylate

Send

Send

Metric Ton KG G Pound L ML

Send

Send