alpha-((4-Aminophenoxy)methyl)-4-phenyl-1-piperazineethanol

Base Information

Chemical Name:alpha-((4-Aminophenoxy)methyl)-4-phenyl-1-piperazineethanol
CAS No.:64511-27-9
Molecular Formula:C19H25 N3 O2
Molecular Weight:327.4207
Hs Code.:
NSC Number:173318

Synonyms:64511-27-9;BRN 0565708;NSC173318;alpha-((4-Aminophenoxy)methyl)-4-phenyl-1-piperazineethanol;1-Piperazineethanol, alpha-((4-aminophenoxy)methyl)-4-phenyl-;NSC 173318;NSC-173318

Suppliers and Price of alpha-((4-Aminophenoxy)methyl)-4-phenyl-1-piperazineethanol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of alpha-((4-Aminophenoxy)methyl)-4-phenyl-1-piperazineethanol

Chemical Property:

Vapor Pressure:3.96E-13mmHg at 25°C
Boiling Point:554.4°C at 760 mmHg
Flash Point:289.1°C
Density:1.188g/cm³
XLogP3:2.2
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:6
Exact Mass:327.19467705
Heavy Atom Count:24
Complexity:347

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CN(CCN1CC(COC2=CC=C(C=C2)N)O)C3=CC=CC=C3

Technology Process of alpha-((4-Aminophenoxy)methyl)-4-phenyl-1-piperazineethanol

There total 5 articles about alpha-((4-Aminophenoxy)methyl)-4-phenyl-1-piperazineethanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 67.0%

: 110808-00-9
1-(4-Phenylazophenoxy)-3-(N-phenylpiperazino)-2-propanol

: 64511-27-9
1-(4-Aminophenoxy)-3-(N-phenylpiperazino)-2-propanol

Guidance literature:: With hydrogen; nickel; In methanol;
DOI:10.1007/BF01146183

Reference yield:

: 64511-26-8
1-(4-nitro-phenoxy)-3-(4-phenyl-piperazin-1-yl)-propan-2-ol

: 64511-27-9
1-(4-Aminophenoxy)-3-(N-phenylpiperazino)-2-propanol

Guidance literature:: With hydrogen; palladium on activated charcoal; In ethanol; for 1h; under 760 Torr;
DOI:10.1021/jm00109a007

Reference yield:

: 100-02-7,78813-13-5,89830-32-0
4-nitro-phenol

: 64511-27-9
1-(4-Aminophenoxy)-3-(N-phenylpiperazino)-2-propanol

Guidance literature:: Multi-step reaction with 3 steps

1: 1 N NaOH / 10 h

2: ethanol / 4 h / Heating

3: H₂ / 10percent Pd/C / ethanol / 1 h / 760 Torr

With sodium hydroxide; hydrogen; palladium on activated charcoal; In ethanol;
DOI:10.1021/jm00109a007