2-AMINO-3-PYRIDINEBUTANOIC ACID

Base Information

• Chemical Name: 2-AMINO-3-PYRIDINEBUTANOIC ACID
• CAS No.: 99461-41-3
• Molecular Formula: C₉H₁₂N₂O₂
• Molecular Weight: 180.206
• Mol file: 99461-41-3.mol

Synonyms:DL-2-amino-4-(3-pyridyl)butyric acid

Chemical Property of 2-AMINO-3-PYRIDINEBUTANOIC ACID

Chemical Property:

Purity/Quality:

99% ^*data from raw suppliers

ALFA-AMINO-3-PYRIDINEBUTANOIC ACID 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-AMINO-3-PYRIDINEBUTANOIC ACID

There total 3 articles about 2-AMINO-3-PYRIDINEBUTANOIC ACID which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3-(3-pyridyl)propan-1-ol (2859-67-8) → DL-2-amino-4-(3-pyridyl)butyric acid (99461-41-3)

Guidance literature:

Multi-step reaction with 3 steps

1: 27 percent / lead tetra-acetate / pyridine / 16 h / Ambient temperature

2: 17 g / ammonium chloride / diethyl ether; H₂O / 1.) 0 deg C, 4 h; 2.) 50 deg C, 7.5 h

3: 12M aq. hydrochloric acid / 1.) 64 h, room temperature; 2.) 30 h, reflux temperature

With lead(IV) acetate; hydrogenchloride; ammonium chloride; In pyridine; diethyl ether; water;

Reference yield:

3-(3-pyridinyl)propionaldehyde (1802-16-0) → DL-2-amino-4-(3-pyridyl)butyric acid (99461-41-3)

Guidance literature:

Multi-step reaction with 2 steps

1: 17 g / ammonium chloride / diethyl ether; H₂O / 1.) 0 deg C, 4 h; 2.) 50 deg C, 7.5 h

2: 12M aq. hydrochloric acid / 1.) 64 h, room temperature; 2.) 30 h, reflux temperature

With hydrogenchloride; ammonium chloride; In diethyl ether; water;

Reference yield:

2-Amino-4-pyridin-3-yl-butyronitrile (99461-40-2) → DL-2-amino-4-(3-pyridyl)butyric acid (99461-41-3)

Guidance literature:

With hydrogenchloride; Yield given; 1.) 64 h, room temperature; 2.) 30 h, reflux temperature;

upstream raw materials:

2-Amino-4-pyridin-3-yl-butyronitrile

3-(3-pyridyl)propan-1-ol

3-(3-pyridinyl)propionaldehyde

Downstream raw materials:

t-butoxycarbonyl-L-2-amino-4-(3-pyridyl)butyric acid

D-2-benzamido-4-(3-pyridyl)butyric acid

L-2-benzamido-4-(3-pyridyl)butyric acid

methyl D-2-benzamido-4-(3-pyridyl)butyrate

Refernces