2-{[(E)-(3-fluorophenyl)methylidene]amino}-2-methylpropan-1-ol

Base Information

• Chemical Name: 2-{[(E)-(3-fluorophenyl)methylidene]amino}-2-methylpropan-1-ol
• CAS No.: 25458-02-0
• Molecular Formula: C11H14 F N O
• Molecular Weight: 195.2334
• Mol file: 25458-02-0.mol

Synonyms:1-Propanol,2-[(m-fluorobenzylidene)amino]-2-methyl- (8CI); NSC 116604

Chemical Property of 2-{[(E)-(3-fluorophenyl)methylidene]amino}-2-methylpropan-1-ol

Chemical Property:

• Vapor Pressure: 0.00108mmHg at 25°C
• Boiling Point: 288.5°Cat760mmHg
• Flash Point: 128.3°C
• Density: 1.02g/cm³

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
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Technology Process of 2-{[(E)-(3-fluorophenyl)methylidene]amino}-2-methylpropan-1-ol

There total 1 articles about 2-{[(E)-(3-fluorophenyl)methylidene]amino}-2-methylpropan-1-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 59.0%

2-Amino-2-methyl-1-propanol (124-68-5) + 3-Fluorobenzaldehyde (456-48-4) → 2-{[1-(3-Fluoro-phenyl)-meth-(Z)-ylidene]-amino}-2-methyl-propan-1-ol (25458-02-0)

Guidance literature:

With 4 A molecular sieve; iodine; In toluene; Ambient temperature;

DOI:10.1016/S0040-4020(01)91431-0

Reference yield:

2-{[1-(3-Fluoro-phenyl)-meth-(Z)-ylidene]-amino}-2-methyl-propan-1-ol (25458-02-0) → 2-(3-Fluoro-benzylamino)-2-methyl-propan-1-ol (22563-92-4)

Guidance literature:

With hydrogen; platinum(IV) oxide; In ethanol;

DOI:10.1002/jps.2600580630

upstream raw materials:

2-Amino-2-methyl-1-propanol

3-Fluorobenzaldehyde

Downstream raw materials:

2-(3-Fluoro-benzylamino)-2-methyl-propan-1-ol

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