4-amino-6,7-bis(4-chlorophenyl)-1H-pyrazino[2,3-c][1,2,6]thiadiazine 2,2-dioxide

Base Information

• Chemical Name: 4-amino-6,7-bis(4-chlorophenyl)-1H-pyrazino[2,3-c][1,2,6]thiadiazine 2,2-dioxide
• CAS No.: 120625-88-9
• Molecular Formula: C₁₇H₁₁Cl₂N₅O₂S
• Molecular Weight: 420.279
• Mol file: 120625-88-9.mol

Synonyms:4-amino-6,7-bis(4-chlorophenyl)-1H-pyrazino[2,3-c][1,2,6]thiadiazine 2,2-dioxide

Chemical Property of 4-amino-6,7-bis(4-chlorophenyl)-1H-pyrazino[2,3-c][1,2,6]thiadiazine 2,2-dioxide

Chemical Property:

Purity/Quality:

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MSDS Files:

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Technology Process of 4-amino-6,7-bis(4-chlorophenyl)-1H-pyrazino[2,3-c][1,2,6]thiadiazine 2,2-dioxide

There total 1 articles about 4-amino-6,7-bis(4-chlorophenyl)-1H-pyrazino[2,3-c][1,2,6]thiadiazine 2,2-dioxide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 40.0%

3,4,5-triamino-1,2,6-thiadiazine 1,1-dioxide (61403-61-0) + 4,4'-dichlorobenzil (3457-46-3,88372-92-3) → 4-amino-6,7-bis(4-chlorophenyl)-1H-pyrazino[2,3-c][1,2,6]thiadiazine 2,2-dioxide (120625-88-9)

Guidance literature:

With hydrogenchloride; In ethanol; for 72h; Heating;

DOI:10.1021/jm981104b

Reference yield: 62.0%

ethyl iodide (75-03-6) + 4-amino-6,7-bis(4-chlorophenyl)-1H-pyrazino[2,3-c][1,2,6]thiadiazine 2,2-dioxide (120625-88-9) → 6,7-bis-(4-chloro-phenyl)-1-ethyl-2,2-dioxo-1,2-dihydro-2λ6-pyrazino[2,3-c][1,2,6]thiadiazin-4-ylamine

Guidance literature:

With triethylamine; In acetone; for 200h; Heating;

DOI:10.1021/jm981104b

Reference yield: 23.0%

4-amino-6,7-bis(4-chlorophenyl)-1H-pyrazino[2,3-c][1,2,6]thiadiazine 2,2-dioxide (120625-88-9) + dimethyl sulfate (77-78-1) → 4-amino-1-methyl-6,7-di-(4'-chlorophenyl)pyrazino<2,3-c>-1,2,6-thiadiazine 2,2-dioxide + 4-amino-8-methyl-6,7-di-(4'-chlorophenyl)pyrazino<2,3-c>-1,2,6-thiadiazine 2,2-dioxide

Guidance literature:

With sodium hydrogencarbonate; In ethanol; for 4h; Ambient temperature;

upstream raw materials:

3,4,5-triamino-1,2,6-thiadiazine 1,1-dioxide

4,4'-dichlorobenzil