1,1-dimethylethyl 4-[(4-bromo-3-fluorophenyl)oxy]-1-piperidinecarboxylate

Base Information

Chemical Name:1,1-dimethylethyl 4-[(4-bromo-3-fluorophenyl)oxy]-1-piperidinecarboxylate
CAS No.:684249-70-5
Molecular Formula:C₁₆H₂₁BrFNO₃
Molecular Weight:374.25
Hs Code.:

Synonyms:1,1-dimethylethyl 4-[(4-bromo-3-fluorophenyl)oxy]-1-piperidinecarboxylate

Suppliers and Price of 1,1-dimethylethyl 4-[(4-bromo-3-fluorophenyl)oxy]-1-piperidinecarboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of 1,1-dimethylethyl 4-[(4-bromo-3-fluorophenyl)oxy]-1-piperidinecarboxylate

Chemical Property:

Purity/Quality:: 99% ^*data from raw suppliers

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Technology Process of 1,1-dimethylethyl 4-[(4-bromo-3-fluorophenyl)oxy]-1-piperidinecarboxylate

There total 2 articles about 1,1-dimethylethyl 4-[(4-bromo-3-fluorophenyl)oxy]-1-piperidinecarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 121219-03-2
4-bromo-3-fluorophenol

: 109384-19-2
t-butyl 4-hydroxy piperidine-1-carboxylate

: 684249-70-5
1,1-dimethylethyl 4-[(4-bromo-3-fluorophenyl)oxy]-1-piperidinecarboxylate

Guidance literature:: With di-tert-butyl-diazodicarboxylate; triphenylphosphine; In tetrahydrofuran; at 20 ℃; for 18h;

Reference yield:

: 348-57-2
2,4-difluorobromobenzene

: 109384-19-2
t-butyl 4-hydroxy piperidine-1-carboxylate

: 684249-70-5
1,1-dimethylethyl 4-[(4-bromo-3-fluorophenyl)oxy]-1-piperidinecarboxylate

: 1006878-92-7
tert-butyl 4-(2-bromo-5-fluorophenoxy)piperidine-1-carboxylate

Guidance literature:: With potassium tert-butylate; In 1,4-dioxane; at 20 ℃; regioselective reaction; Inert atmosphere;
DOI:10.1016/j.tetlet.2009.03.204