dibenzyl 3-(N-(benzyloxy)acetamido)-1-hydroxypropylphosphonate

Base Information

Chemical Name:dibenzyl 3-(N-(benzyloxy)acetamido)-1-hydroxypropylphosphonate
CAS No.:1415747-25-9
Molecular Formula:C₂₆H₃₀NO₆P
Molecular Weight:483.501
Hs Code.:

Synonyms:dibenzyl 3-(N-(benzyloxy)acetamido)-1-hydroxypropylphosphonate

Suppliers and Price of dibenzyl 3-(N-(benzyloxy)acetamido)-1-hydroxypropylphosphonate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of dibenzyl 3-(N-(benzyloxy)acetamido)-1-hydroxypropylphosphonate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of dibenzyl 3-(N-(benzyloxy)acetamido)-1-hydroxypropylphosphonate

There total 4 articles about dibenzyl 3-(N-(benzyloxy)acetamido)-1-hydroxypropylphosphonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

: 538-60-3
dibenzyl hydrogen phosphite

: 1415747-26-0
N-(benzyloxy)-N-(2-formylethyl)acetamide

: 1415747-25-9
dibenzyl 3-(N-(benzyloxy)acetamido)-1-hydroxypropylphosphonate

Guidance literature:: dibenzyl hydrogen phosphite; With lithium hexamethyldisilazane; In tetrahydrofuran; at -78 ℃; for 0.25h;

N-(benzyloxy)-N-(2-formylethyl)acetamide; In tetrahydrofuran; at -78 ℃; for 0.25h;
DOI:10.1021/jm301577q

Reference yield:

: 1373213-82-1
tert-butyl N-(benzyloxy)-N-(but-3-enyl)carbamate

: 1415747-25-9
dibenzyl 3-(N-(benzyloxy)acetamido)-1-hydroxypropylphosphonate

Guidance literature:: Multi-step reaction with 3 steps

1.1: sodium iodide / methanol; acetonitrile / 1 h / 20 °C

1.2: 1.08 h / 0 - 20 °C

2.1: potassium osmate(VI) dihydrate; sodium periodate / tetrahydrofuran; water / 4 h / Darkness

3.1: lithium hexamethyldisilazane / tetrahydrofuran / 0.25 h / -78 °C

3.2: 0.25 h / -78 °C

With potassium osmate(VI) dihydrate; sodium periodate; sodium iodide; lithium hexamethyldisilazane; In tetrahydrofuran; methanol; water; acetonitrile;
DOI:10.1021/jm301577q

Reference yield:

: 79722-21-7
tert-butyl N-(benzyloxy)carbamate

: 1415747-25-9
dibenzyl 3-(N-(benzyloxy)acetamido)-1-hydroxypropylphosphonate

Guidance literature:: Multi-step reaction with 4 steps

1.1: sodium hydride / N,N-dimethyl-formamide; mineral oil / 0.5 h / 20 °C

1.2: 1.5 h

2.1: sodium iodide / methanol; acetonitrile / 1 h / 20 °C

2.2: 1.08 h / 0 - 20 °C

3.1: potassium osmate(VI) dihydrate; sodium periodate / tetrahydrofuran; water / 4 h / Darkness

4.1: lithium hexamethyldisilazane / tetrahydrofuran / 0.25 h / -78 °C

4.2: 0.25 h / -78 °C

With potassium osmate(VI) dihydrate; sodium periodate; sodium hydride; sodium iodide; lithium hexamethyldisilazane; In tetrahydrofuran; methanol; water; N,N-dimethyl-formamide; acetonitrile; mineral oil;
DOI:10.1021/jm301577q