2-<3-benzyl-6-oxo-2-thia-4,7-diaza-(1R,5R)-bicyclo-<3.2.0>-hept-3-en-7-yl>-benzyl acetate

Base Information

Chemical Name:2-<3-benzyl-6-oxo-2-thia-4,7-diaza-(1R,5R)-bicyclo-<3.2.0>-hept-3-en-7-yl>-benzyl acetate
CAS No.:76227-78-6
Molecular Formula:C₂₀H₁₈N₂O₃S
Molecular Weight:366.441
Hs Code.:

Synonyms:2-<3-benzyl-6-oxo-2-thia-4,7-diaza-(1R,5R)-bicyclo-<3.2.0>-hept-3-en-7-yl>-benzyl acetate

Suppliers and Price of 2-<3-benzyl-6-oxo-2-thia-4,7-diaza-(1R,5R)-bicyclo-<3.2.0>-hept-3-en-7-yl>-benzyl acetate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 2-<3-benzyl-6-oxo-2-thia-4,7-diaza-(1R,5R)-bicyclo-<3.2.0>-hept-3-en-7-yl>-benzyl acetate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 2-<3-benzyl-6-oxo-2-thia-4,7-diaza-(1R,5R)-bicyclo-<3.2.0>-hept-3-en-7-yl>-benzyl acetate

There total 4 articles about 2-<3-benzyl-6-oxo-2-thia-4,7-diaza-(1R,5R)-bicyclo-<3.2.0>-hept-3-en-7-yl>-benzyl acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 47.0%

: 34103-69-0
(1E,5R)-3-Phenylmethyl-4-thia-2,6-diazabicyclo[3.2.0]hept-2-en-7-one

: 5437-45-6
Benzyl bromoacetate

: 76227-78-6
2-<3-benzyl-6-oxo-2-thia-4,7-diaza-(1R,5R)-bicyclo-<3.2.0>-hept-3-en-7-yl>-benzyl acetate

Guidance literature:: With N-benzyl-trimethylammonium hydroxide; In N,N-dimethyl-formamide; at -30 - -20 ℃;
DOI:10.1016/S0040-4039(00)77414-4

Reference yield:

: 69-57-8
Penicillin G sodium

: 76227-78-6
2-<3-benzyl-6-oxo-2-thia-4,7-diaza-(1R,5R)-bicyclo-<3.2.0>-hept-3-en-7-yl>-benzyl acetate

Guidance literature:: Multi-step reaction with 4 steps

1: 1) NaIO₄ / 1) H₂O; 2) NEt₃, DMF, 20 deg C

2: 65 percent Chromat_. / MgSO₄, (CH₃O)3P / benzene / 40 h / Heating

3: 74 percent / KMnO₄, MgSO₄ / H₂O; ethanol / 15 - 20 °C

4: 1) NaH / 1) DMF, 0 deg C; 2) DMF, 1 h, 0 deg C; 2 h, r. t.

With potassium permanganate; sodium periodate; sodium hydride; magnesium sulfate; phosphorous acid trimethyl ester; In ethanol; water; benzene;
DOI:10.1016/S0040-4020(01)92143-X

Reference yield:

: 54275-92-2
6-β-phenylacetamidopenicillanic acid-(1S)-oxide

: 76227-78-6
2-<3-benzyl-6-oxo-2-thia-4,7-diaza-(1R,5R)-bicyclo-<3.2.0>-hept-3-en-7-yl>-benzyl acetate

Guidance literature:: Multi-step reaction with 3 steps

1: 65 percent Chromat_. / MgSO₄, (CH₃O)3P / benzene / 40 h / Heating

2: 74 percent / KMnO₄, MgSO₄ / H₂O; ethanol / 15 - 20 °C

3: 1) NaH / 1) DMF, 0 deg C; 2) DMF, 1 h, 0 deg C; 2 h, r. t.

With potassium permanganate; sodium hydride; magnesium sulfate; phosphorous acid trimethyl ester; In ethanol; water; benzene;
DOI:10.1016/S0040-4020(01)92143-X