34103-69-0

Usage

Uses

Since the provided materials do not specify the exact applications of 4-Thia-2,6-diazabicyclo[3.2.0]hept-2-en-7-one, 3-(phenylmethyl)-, (1R-cis)-, the following uses are inferred based on its structural features and potential for pharmacological or biological activities:
Used in Pharmaceutical Industry:
4-Thia-2,6-diazabicyclo[3.2.0]hept-2-en-7-one, 3-(phenylmethyl)-, (1R-cis)may be used as a pharmaceutical intermediate or a lead compound for the development of new drugs. Its unique structure and functional groups could be exploited to target specific biological pathways or receptors, potentially leading to the discovery of novel therapeutic agents.
Used in Chemical Research:
In the field of chemical research, 4-Thia-2,6-diazabicyclo[3.2.0]hept-2-en-7-one, 3-(phenylmethyl)-, (1R-cis)could serve as a model compound for studying the synthesis, reactivity, and properties of heterocyclic compounds. Its stereochemistry and functional groups may also be of interest in understanding the relationship between molecular structure and biological activity.
Used in Material Science:
4-Thia-2,6-diazabicyclo[3.2.0]hept-2-en-7-one, 3-(phenylmethyl)-, (1R-cis)-'s unique structure and functional groups may also find applications in material science, where it could be used to develop new materials with specific properties, such as conductivity, magnetism, or catalytic activity.

Upstream product

• 108-24-7 acetic anhydride 
• 67529-66-2 2-((1R)-3-benzyl-7-oxo-(1rH,5cH)-4-thia-2,6-diaza-bicyclo[3.2.0]hept-2-en-6-yl)-3-methyl-but-2-enoic acid methyl ester 
• 61990-36-1 (R)-2-((1R)-3-benzyl-7-oxo-(1rH,5cH)-4-thia-2,6-diaza-bicyclo[3.2.0]hept-2-en-6-yl)-3-methyl-but-3-enoic acid methyl ester 
• 24652-72-0 methyl 6β-(phenylacetamido)penicillanate 1β-oxide 
• 91177-12-7 (R)-2-((1R,5R)-3-Benzyl-7-oxo-4-thia-2,6-diaza-bicyclo[3.2.0]hept-2-en-6-yl)-3-methyl-but-3-enoic acid 
• 54275-92-2 6-β-phenylacetamidopenicillanic acid-(1S)-oxide 
• 69-57-8 Penicillin G sodium 
• 269742-76-9 (3S,4S)-3-N-(Benzyloxycarbonyl)-3-N-(phenylacetoxy)amino-4-acetoxyazetidin-2-one 
• 83873-54-5 (3S,4S)-4-acetoxy-3-phenylacetamido-1-tert-butyldi methylsilyl-azetidin-2-one 
• 199385-33-6 (3S)-3-N-(Benzyloxycarbonyl)-3-N-(phenylacetoxy)aminoazetidin-2-one 
• 103-80-0 phenylacetyl chloride 
• 85027-68-5 (2S-trans)-N-<2-(acetyloxy)-4-oxo-3-azetidinyl>benzeneacetamide 
• 87996-76-7 2-((1R,5R)-3-Benzyl-7-oxo-4-thia-2,6-diaza-bicyclo[3.2.0]hept-2-en-6-yl)-3-methyl-but-2-enoic acid benzyl ester 
• 85460-53-3 Acetic acid 1-((1R,5R)-3-benzyl-7-oxo-4-thia-2,6-diaza-bicyclo[3.2.0]hept-2-en-6-yl)-2-methyl-allyl ester 

Downstream Products

• 69880-97-3 (R)-((1R)-3-benzyl-7-oxo-(1rH,5cH)-4-thia-2,6-diaza-bicyclo[3.2.0]hept-2-en-6-yl)-phenyl-acetic acid methyl ester 
• 53879-34-8 2-((1R)-3-benzyl-7-oxo-(1rH,5cH)-4-thia-2,6-diaza-bicyclo[3.2.0]hept-2-en-6-ylmethyl)-acrylic acid tert-butyl ester 
• 53879-32-6 ((1R)-3-benzyl-7-oxo-(1rH,5cH)-4-thia-2,6-diaza-bicyclo[3.2.0]hept-2-en-6-yl)-malonic acid dimethyl ester 
• 76227-79-7 2-<3-benzyl-6-oxo-2-thia-4,7-diaza-(1R,5R)-bicyclo-<3.2.0>-hept-3-en-7-yl>-t-butyl acetate 
• 76227-76-4 ((2R,3R)-4-Oxo-3-phenylacetylamino-azetidin-2-ylsulfanylcarbonyl)-acetic acid methyl ester 
• 76227-75-3 2-((2R,3R)-4-Oxo-3-phenylacetylamino-azetidin-2-ylsulfanyl)-malonic acid dimethyl ester 
• 76227-74-2 Diazo-((2R,3R)-4-oxo-3-phenylacetylamino-azetidin-2-ylsulfanylcarbonyl)-acetic acid methyl ester 
• 87996-92-7 (6R)-phenylacetamido-2-benzoyloxy-(5R)-penem-3-p-nitrobenzyl-carboxylate 
• 78815-25-5 (6R)-phenylacetamido-2-methoxy-(5R)-penem-3-p-nitrobenzyl-carboxylate 
• 78815-06-2 2-((2R,3R)-2-Mercapto-4-oxo-3-phenylacetylamino-azetidin-1-yl)-malonic acid mono-(4-nitro-benzyl) ester 
• 78815-20-0 2-((2R,3R)-2-Mercapto-4-oxo-3-phenylacetylamino-azetidin-1-yl)-malonic acid monobenzhydryl ester 
• 78815-29-9 (6R)-phenylacetamido-2-benzoyloxy-(5R)-penem-3-t-butyl-carboxylate 
• 78815-23-3 2-oxo-bisnorpenicillin G-3-p-nitrobenzyl carboxylate 
• 78815-03-9 2-<3-benzyl-6-oxo-2-thia-4,7-diaza-(1R,5R)-bicyclo-<3.2.0>-hept-3-en-7-yl>-mono-p-nitrobenzyl malonate 

Relevant academic research and scientific papers

A total synthesis of (1R,5R)-3-phenylmethyl-4-thia-2,6-diazabicyclo [3.2.0]hept-2-en-7-one, a useful intermediate for the preparation of penem and cepham derivatives

The preparation of the thiazoline (1R,5R)-3-phenylmethyl-4-thia-2,6- diazabicyclo [3.2.0]hept-2-en-7-one (1) is presented. This compound, which has been extensively used as an intermediate for the synthesis of penems and cephams, has been obtained starting from a C-4 unsubstituted azetidinone by means of facile processes while chirality has been obtained through enzymatic resolution.

Synthesis of 2-oxo-penams and penems from penicillin G

Using Penicillin G as starting material, general methods of synthesis for the 2-oxo-penam skeleton have been established. Compounds 7 represent a new group of strained penicillin derivatives. They can be readily transformed into 2-alkoxy 17 or benzoyloxypenems 18.