3-(4-methoxybenzoyl)-2-methylbenzofuran-5,6-dicarbonitrile

Base Information

• Chemical Name: 3-(4-methoxybenzoyl)-2-methylbenzofuran-5,6-dicarbonitrile
• CAS No.: 1192656-34-0
• Molecular Formula: C₁₉H₁₂N₂O₃
• Molecular Weight: 316.316
• Mol file: 1192656-34-0.mol

Synonyms:3-(4-methoxybenzoyl)-2-methylbenzofuran-5,6-dicarbonitrile

Chemical Property of 3-(4-methoxybenzoyl)-2-methylbenzofuran-5,6-dicarbonitrile

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-(4-methoxybenzoyl)-2-methylbenzofuran-5,6-dicarbonitrile

There total 1 articles about 3-(4-methoxybenzoyl)-2-methylbenzofuran-5,6-dicarbonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 64.0%

C11H11O3(1-)*Na(1+) + 4-bromo-5-nitrophthalonitrile (206268-72-6) → 3-(4-methoxybenzoyl)-2-methylbenzofuran-5,6-dicarbonitrile (1192656-34-0)

Guidance literature:

C₁₁H₁₁O₃^(1-)*Na⁽¹⁺⁾; 4-bromo-5-nitrophthalonitrile; In N,N-dimethyl-formamide; at 25 - 35 ℃;

With hydrogenchloride; In N,N-dimethyl-formamide; stereoselective reaction;

DOI:10.1016/j.mencom.2009.11.013

Reference yield: 90.0%

3-(4-methoxybenzoyl)-2-methylbenzofuran-5,6-dicarbonitrile (1192656-34-0) + phenylhydrazine (100-63-0) → 4-hydroxy-5-[3-(4-methoxyphenyl)-5-methyl-1-phenyl-1H-pyrazol-4-yl]benzene-1,2-dicarbonitrile

Guidance literature:

In ethanol; at 40 - 78 ℃;

DOI:10.1134/S1070428015050103

Reference yield: 76.0%

3-(4-methoxybenzoyl)-2-methylbenzofuran-5,6-dicarbonitrile (1192656-34-0) → 4-hydroxy-5-[5-methyl-3-(4-methoxyphenyl)-1H-pyrazol-4-yl]benzene-1,2-dicarbonitrile

Guidance literature:

With hydrazine; In ethanol; at 40 - 78 ℃;

DOI:10.1134/S1070428015050103

upstream raw materials:

4-bromo-5-nitrophthalonitrile

Downstream raw materials:

C₂₂H₁₇N₃O₃

4-hydroxy-5-{1-[hydroxy(4-methoxyphenyl)methyl]propyl}phthalonitrile

3-[hydroxy(4-methoxyphenyl)methyl]-2-methyl-1-benzofuran-5,6-dicarbonitrile