2-({2-[(1-benzofuran-2-ylsulfonyl)amino]-4-chlorophenyl}sulfanyl)benzoic acid

Base Information

Chemical Name:2-({2-[(1-benzofuran-2-ylsulfonyl)amino]-4-chlorophenyl}sulfanyl)benzoic acid
CAS No.:1451261-79-2
Molecular Formula:C₂₁H₁₄ClNO₅S₂
Molecular Weight:459.931
Hs Code.:

Synonyms:2-({2-[(1-benzofuran-2-ylsulfonyl)amino]-4-chlorophenyl}sulfanyl)benzoic acid

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Chemical Property of 2-({2-[(1-benzofuran-2-ylsulfonyl)amino]-4-chlorophenyl}sulfanyl)benzoic acid

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Technology Process of 2-({2-[(1-benzofuran-2-ylsulfonyl)amino]-4-chlorophenyl}sulfanyl)benzoic acid

There total 5 articles about 2-({2-[(1-benzofuran-2-ylsulfonyl)amino]-4-chlorophenyl}sulfanyl)benzoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: C₂₂H₁₆ClNO₅S₂

: 1451261-79-2
2-({2-[(1-benzofuran-2-ylsulfonyl)amino]-4-chlorophenyl}sulfanyl)benzoic acid

Guidance literature:: With methanol; sodium hydroxide; at 100 ℃; for 0.25h;

Reference yield:

: 92161-65-4
methyl 2-((4-chloro-2-nitrophenyl)thio)benzoate

: 1451261-79-2
2-({2-[(1-benzofuran-2-ylsulfonyl)amino]-4-chlorophenyl}sulfanyl)benzoic acid

Guidance literature:: Multi-step reaction with 3 steps

1: ammonium chloride; zinc / water; methanol / 0.5 h / 20 °C

2: pyridine / 40 h / 20 °C

3: sodium hydroxide; methanol / 0.25 h / 100 °C

With pyridine; methanol; ammonium chloride; sodium hydroxide; zinc; In methanol; water;

Reference yield:

: 4892-02-8
Methyl thiosalicylate

: 1451261-79-2
2-({2-[(1-benzofuran-2-ylsulfonyl)amino]-4-chlorophenyl}sulfanyl)benzoic acid

Guidance literature:: Multi-step reaction with 4 steps

1: sodium hydroxide / methanol / 2 h / 20 °C

2: ammonium chloride; zinc / water; methanol / 0.5 h / 20 °C

3: pyridine / 40 h / 20 °C

4: sodium hydroxide; methanol / 0.25 h / 100 °C

With pyridine; methanol; ammonium chloride; sodium hydroxide; zinc; In methanol; water;