Technology Process of Dithiocarbonic acid O-[(2R,3R,4S,5R,6R)-4,5-bis-benzyloxy-2-(tert-butyl-diphenyl-silanyloxymethyl)-6-methoxy-tetrahydro-pyran-3-yl] ester S-methyl ester
There total 7 articles about Dithiocarbonic acid O-[(2R,3R,4S,5R,6R)-4,5-bis-benzyloxy-2-(tert-butyl-diphenyl-silanyloxymethyl)-6-methoxy-tetrahydro-pyran-3-yl] ester S-methyl ester which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 1.) NaH, 2.) tetrabutylammonium iodide / 1.) THF, RT, 1 h, 2.) THF, RT, 24 h
2: 83 percent / Amberlyst 15 H+ / methanol / 4 h / Ambient temperature
3: 100 percent / imidazole / tetrahydrofuran; dimethylformamide / 24 h / 50 °C
4: 1.) sodium bis(trimethylsilyl)amide / 1.) THF, -78 deg C, 15 min, 2.) THF, from -78 deg C to RT, 60 min
With
1H-imidazole; Amberlyst 15 H+; sodium hexamethyldisilazane; tetra-(n-butyl)ammonium iodide; sodium hydride;
In
tetrahydrofuran; methanol; N,N-dimethyl-formamide;
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 1.) NaH, 2.) tetrabutylammonium iodide / 1.) THF, RT, 1 h, 2.) THF, RT, 24 h
2: 83 percent / Amberlyst 15 H+ / methanol / 4 h / Ambient temperature
3: 100 percent / imidazole / tetrahydrofuran; dimethylformamide / 24 h / 50 °C
4: 1.) sodium bis(trimethylsilyl)amide / 1.) THF, -78 deg C, 15 min, 2.) THF, from -78 deg C to RT, 60 min
With
1H-imidazole; Amberlyst 15 H+; sodium hexamethyldisilazane; tetra-(n-butyl)ammonium iodide; sodium hydride;
In
tetrahydrofuran; methanol; N,N-dimethyl-formamide;
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 100 percent / imidazole / tetrahydrofuran; dimethylformamide / 24 h / 50 °C
2: 1.) sodium bis(trimethylsilyl)amide / 1.) THF, -78 deg C, 15 min, 2.) THF, from -78 deg C to RT, 60 min
With
1H-imidazole; sodium hexamethyldisilazane;
In
tetrahydrofuran; N,N-dimethyl-formamide;
