N-(4,5-Dihydro-2-thiazolyl)-2-(4-isobutylphenyl)propionamide

Base Information

• Chemical Name: N-(4,5-Dihydro-2-thiazolyl)-2-(4-isobutylphenyl)propionamide
• CAS No.: 59512-32-2
• Molecular Formula: C₁₆H₂₂N₂OS
• Molecular Weight: 290.429
• DSSTox Substance ID: DTXSID90974928
• Nikkaji Number: J87.433G
• Mol file: 59512-32-2.mol

Synonyms:BRN 0541694;59512-32-2;N-(4,5-Dihydro-2-thiazolyl)-2-(4-isobutylphenyl)propionamide;Propionamide, N-(4,5-dihydro-2-thiazolyl)-2-(4-isobutylphenyl)-;DTXSID90974928;N-(4,5-Dihydrothiazol-2-yl)-2-(4-isobutylphenyl)propionamide;LS-124153;Benzeneacetamide, N-(4,5-dihydro-2-thiazolyl)-.alpha.-methyl-4-(2-methylpropyl)-;N-(4,5-Dihydro-1,3-thiazol-2-yl)-2-[4-(2-methylpropyl)phenyl]propanimidic acid

Chemical Property of N-(4,5-Dihydro-2-thiazolyl)-2-(4-isobutylphenyl)propionamide

Chemical Property:

• Boiling Point: °Cat760mmHg
• Flash Point: °C
• PSA: 70.25000
• Density: 1.15g/cm³
• LogP: 3.48350
• XLogP3: 3.7
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 5
• Exact Mass: 290.14528450
• Heavy Atom Count: 20
• Complexity: 360

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(C)CC1=CC=C(C=C1)C(C)C(=O)NC2=NCCS2

Technology Process of N-(4,5-Dihydro-2-thiazolyl)-2-(4-isobutylphenyl)propionamide

There total 1 articles about N-(4,5-Dihydro-2-thiazolyl)-2-(4-isobutylphenyl)propionamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4,5-Dihydro-thiazol-2-ylamin (1779-81-3) + (+/-)-2-(4-isobutylphenyl)propanoyl chloride (71381-91-4,114978-05-1,115588-20-0,34715-60-1) → N-(4,5-dihydro-thiazol-2-yl)-2-(4-isobutyl-phenyl)-propionamide (59512-32-2)

Guidance literature:

With triethylamine; In 1,4-dioxane; for 2h; Heating;

upstream raw materials:

4,5-Dihydro-thiazol-2-ylamin

(+/-)-2-(4-isobutylphenyl)propanoyl chloride