Triphosphoric acid

Base Information

• Chemical Name: Triphosphoric acid
• CAS No.: 10380-08-2
• Deprecated CAS: 887325-62-4,959700-29-9,959700-29-9
• Molecular Formula: H5O10 P3
• Molecular Weight: 257.955
• European Community (EC) Number: 233-840-3
• UNII: NU43IAG5BC
• DSSTox Substance ID: DTXSID7047483
• Nikkaji Number: J236.802A
• Wikipedia: Triphosphoric_acid
• Wikidata: Q2823316
• ChEMBL ID: CHEMBL1230191
• Mol file: 10380-08-2.mol

Synonyms:pentapotassium triphosphate;potassium triphosphate;sodium triphosphate;sodium tripolyphosphate;sodium tripolyphosphate anhydrous;tetrasodium tripolyphosphate;triphosphate;triphosphoric acid;triphosphoric acid, 99Tc-labeled cpd;triphosphoric acid, pentapotassium salt;triphosphoric acid, pentasodium salt;triphosphoric acid, sodium salt;triphosphoric acid, sodium, potassium salt;tripolyphosphate

Chemical Property of Triphosphoric acid

Chemical Property:

• Boiling Point: °Cat760mmHg
• Flash Point: °C
• PSA: 200.25000
• Density: 2.548g/cm³
• LogP: -0.69460
• XLogP3: -4.3
• Hydrogen Bond Donor Count: 5
• Hydrogen Bond Acceptor Count: 10
• Rotatable Bond Count: 4
• Exact Mass: 257.90955735
• Heavy Atom Count: 13
• Complexity: 272

Purity/Quality:

98%,99%, ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Chemical Classes: Toxic Gases & Vapors -> Acids, Inorganic
• Canonical SMILES: OP(=O)(O)OP(=O)(O)OP(=O)(O)O

Technology Process of Triphosphoric acid

There total 33 articles about Triphosphoric acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 37.0%

4-methoxy-7-morpholin-4-yl-benzothiazol-2-yl-amine (383865-57-4) → N-(4-Methoxy-7-morpholin-4-yl-benzothiazol-2-yl)-2-phenyl-acetamide + phenylacetyl chloride (103-80-0)

Guidance literature:

Reference yield: 34.0%

benzeneacetic acid methyl ester (101-41-7) → phenylacetyl chloride (103-80-0)

Guidance literature:

With iodine; phosphorus trichloride; at 160 ℃; for 48h; Schlenk technique; Sealed tube;

DOI:10.1002/ejoc.202100630

Reference yield:

4-chloro-1,3,4-triphenyl-butan-2-one (937611-56-8) → stilbene (588-59-0) + phenylacetyl chloride (103-80-0)

Guidance literature:

upstream raw materials:

phosphoric acid

trimetaphosphoric acid

M-P₂O₅ (monomeric P₄O₁₀)

pyrophosphoric acid

Downstream raw materials:

phosphoric acid

pyrophosphoric acid

Phosphate

Refernces

• 1、 Seamon, Kyle J.,Hansen, Erik C.,Kadina, Anastasia P.,Kashemirov, Boris A.,McKenna, Charles E.,Bumpus, Namandjé N.,Stivers, James T.. "Small molecule inhibition of SAMHD1 dNTPase by tetramer destabilization". . p. 9822 - 9825. Retrieved 2014.
• 2、 Li, Fangshao,Wu, Xiaofang,Guo, Fengzhe,Tang, Zi-Long,Xiao, Jing. "One-step Conversion of Amides and Esters to Acid Chlorides with PCl3". supporting information. p. 4314 - 4317. Retrieved 2021/07/16.
• 3、 Tng, Jiahui,Lim, Junxian,Wu, Kai-Chen,Lucke, Andrew J.,Xu, Weijun,Reid, Robert C.,Fairlie, David P.. "Achiral Derivatives of Hydroxamate AR-42 Potently Inhibit Class i HDAC Enzymes and Cancer Cell Proliferation". . p. 5956 - 5971. Retrieved 2020/06/05.