2,2-diallyl-1-benzylazepane

Base Information

• Chemical Name: 2,2-diallyl-1-benzylazepane
• CAS No.: 1017320-18-1
• Molecular Formula: C₁₉H₂₇N
• Molecular Weight: 269.43
• Mol file: 1017320-18-1.mol

Synonyms:2,2-diallyl-1-benzylazepane

Chemical Property of 2,2-diallyl-1-benzylazepane

Chemical Property:

Purity/Quality:

Safty Information:

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• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2,2-diallyl-1-benzylazepane

There total 2 articles about 2,2-diallyl-1-benzylazepane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

1-benzyl-7-methylsulfanyl-3,4,5,6-tetrahydro-2H-azepinium iodide (1017237-89-6) + allylmagnesium bromide (1730-25-2) → 2,2-diallyl-1-benzylazepane (1017320-18-1)

Guidance literature:

In tetrahydrofuran; at 0 - 20 ℃; for 5h; Inert atmosphere;

DOI:10.1021/ol800145h

Reference yield: 77.0%

1-Benzyl-hexahydro-azepin-2-on (33241-96-2) + allylmagnesium bromide (1730-25-2) → 2,2-diallyl-1-benzylazepane (1017320-18-1)

Guidance literature:

1-Benzyl-hexahydro-azepin-2-on; With 2,6-di-tert-butyl-4-methylpyridine; trifluoromethylsulfonic anhydride; In dichloromethane; at -78 ℃; for 0.75h; Inert atmosphere;

allylmagnesium bromide; In dichloromethane; at -78 - 20 ℃; for 3h; Inert atmosphere;

DOI:10.1002/chem.201302096

Reference yield: 91.0%

2,2-diallyl-1-benzylazepane (1017320-18-1) → 6-benzyl-6-azaspiro[4.6]undec-2-ene (1017237-98-7)

Guidance literature:

2,2-diallyl-1-benzylazepane; With acetyl chloride; In methanol; at 20 ℃; for 0.5h; Inert atmosphere;

With tricyclohexylphosphine[1,3-bis(2,4,6-trimethylphenyl)-4,5-dihydroimidazol-2-ylidine][benzylidene]ruthenium(II) dichloride; In dichloromethane; for 2h; Reflux; Inert atmosphere;

DOI:10.1002/chem.201302096

upstream raw materials:

1-benzyl-7-methylsulfanyl-3,4,5,6-tetrahydro-2H-azepinium iodide

allylmagnesium bromide

1-Benzyl-hexahydro-azepin-2-on

Downstream raw materials:

6-benzyl-6-azaspiro[4.6]undec-2-ene