33241-96-2

Basic information

• Product Name: 1-Benzyl-hexahydro-azepin-2-on
• Synonyms: 1-Benzyl-hexahydro-azepin-2-on;2H-Azepin-2-one, hexahydro-1-(phenylmethyl)-;1-Benzyl-2-Azepanone(WXC03245)
• CAS NO: 33241-96-2
• Molecular Formula: C₁₃H₁₇NO
• Molecular Weight: 203.28018
• Mol File: 33241-96-2.mol
• Article Data: 39

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1-Benzyl-hexahydro-azepin-2-on(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Benzyl-hexahydro-azepin-2-on(33241-96-2)
• EPA Substance Registry System: 1-Benzyl-hexahydro-azepin-2-on(33241-96-2)

Safety Data

• Hazardous Substances Data: 33241-96-2(Hazardous Substances Data)

Usage

Physical state

Colorless or white solid

Solubility

Soluble in organic solvents

Pharmaceutical industry use

Intermediate in the synthesis of various drugs

Sedative properties

Potential candidate for the development of new medications for the treatment of anxiety and sleep disorders

Anxiolytic properties

Potential candidate for the development of new medications for the treatment of anxiety and sleep disorders

Applications in materials science

Due to its unique structure and reactivity

Applications in organic chemistry

Due to its unique structure and reactivity

Potential uses

Wide range of potential uses in the synthesis of various pharmaceuticals and materials

Upstream product

• 20422-13-3 1-benzylazepane 
• 201230-82-2 carbon monoxide 
• 54436-58-7 N-benzylpent-4-en-1-amine 
• 105-60-2 caprolactam 
• 100-39-0 benzyl bromide 
• 108-88-3 toluene 
• 100-52-7 benzaldehyde 
• 60-32-2 6-aminohexanoic acid 
• 19434-64-1 α-chlorooxohexamethylenimine 
• 100-46-9 benzylamine 
• 111-49-9 hexamethylene imine 
• 58170-50-6 pent-4-enoic acid benzylamide 
• 108-94-1 cyclohexanone 
• 622-79-7 benzyl azide 

Downstream Products

• 78521-49-0 6-[benzyl-(toluene-4-sulfonyl)-amino]-hexanoic acid 
• 115860-52-1 5-(1-benzyl-2-hexahydroazepinylidene)-2,2-dimethyl-1,3-dioxane-4,6-dione 
• 85175-02-6 1-Benzyl-3-(2-hydroxybenzoyl)perhydro-2-azepinon 
• 20422-13-3 1-benzylazepane 
• 108046-37-3 β-hydroxy-ε-caprolactam 
• 108046-36-2 N-benzyl hydroxy-5 caprolactame 
• 165257-10-3 1-benzyl-3-phenylseleno-(1H)-hexahydroazepin-2-one 
• 593278-61-6 1-benzyl-3,3-dichloroazepan-2-one 
• 914402-74-7 N-benzyl-2-vinylazepane 
• 359582-72-2 1-benzyl-2-{(4-bromo-2-cyanophenyl) imino} hexahydro-1H-azepine 
• 17642-90-9 1-benzylhexahydro-2H-azepine-2-thione 
• 109859-89-4 C₁₄H₁₇NO₃ 
• 1017238-02-6 1-benzyl-2,2-dibutylazepane 
• 1017237-89-6 1-benzyl-7-methylsulfanyl-3,4,5,6-tetrahydro-2H-azepinium iodide 

Relevant articles and documents

Synthesis of Lactams by Reductive Amination of Carbonyl Derivatives with ω-Amino Fatty Acids under Hydrosilylation Conditions

An efficient method for the preparation of lactams from ω-amino fatty acids under hydrosilylation is described. A variety of lactams such as pyrrolidinones, piperidinones and 2-azepanones were selectively synthesised in moderate to excellent yields (29 examples, up to 95 % isolated yields) with a good functional group tolerance. Notably, no metallic based catalyst was required to perform this transformation.

Purification method for DL-alpha-amino caprolactam

The invention belongs to the technical field of the organic matter purification technology, and particularly relates to a purification method for DL-alpha-amino caprolactam. The preparation method comprises the following steps: S1: dissolving alpha-halogenated caprolactam and benzylamine in an organic solvent, adding alkali, controlling reaction temperature, and reacting to generate N-benzyl-DL-alpha-amino caprolactam; S2: adding the N-benzyl-DL-alpha-amino caprolactam generated by reaction in S1 into a reflux solvent, then, adding a catalyst and a hydrogen supply reagent, and carrying out reflux reaction to prepare a DL-alpha-amino caprolactam coarse product; S3: heating and dissolving the prepared DL-alpha-amino caprolactam coarse product by a recrystallization solvent, removing impurities during hotness, cooling, filtering, and taking solid, i.e. purified DL-alpha-amino caprolactam, wherein the recrystallization solvent is a mixed solvent obtained by mixing ethyl acetate, tetrahydrofuran and cyclohexanone at the mass ratio of (15-20):(6-8):5.

NOVEL, HIGHLY ACTIVE PYRAZOLO-PIPERIDINE SUBSTITUTED INDOLE-2-CARBOXAMIDES ACTIVE AGAINST THE HEPATITIS B VIRUS (HBV)

The present invention relates generally to novel antiviral agents. Specifically, the present invention relates to compounds which can inhibit the protein(s) encoded by hepatitis B virus (HBV) or interfere with the function of the HBV replication cycle, compositions comprising such compounds, methods for inhibiting HBV viral replication, methods for treating or preventing HBV infection, and processes and intermediates for making the compounds.