2-[2-chloro-4-[5-(3,5-dichlorophenyl)-5-(trifluoromethyl)-4H-isothiazol-3-yl]phenyl]sulfanylacetic acid

Base Information

Chemical Name:2-[2-chloro-4-[5-(3,5-dichlorophenyl)-5-(trifluoromethyl)-4H-isothiazol-3-yl]phenyl]sulfanylacetic acid
CAS No.:1610614-68-0
Molecular Formula:C₁₈H₁₁Cl₃F₃NO₂S₂
Molecular Weight:500.777
Hs Code.:

Synonyms:2-[2-chloro-4-[5-(3,5-dichlorophenyl)-5-(trifluoromethyl)-4H-isothiazol-3-yl]phenyl]sulfanylacetic acid

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Chemical Property of 2-[2-chloro-4-[5-(3,5-dichlorophenyl)-5-(trifluoromethyl)-4H-isothiazol-3-yl]phenyl]sulfanylacetic acid

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Technology Process of 2-[2-chloro-4-[5-(3,5-dichlorophenyl)-5-(trifluoromethyl)-4H-isothiazol-3-yl]phenyl]sulfanylacetic acid

There total 1 articles about 2-[2-chloro-4-[5-(3,5-dichlorophenyl)-5-(trifluoromethyl)-4H-isothiazol-3-yl]phenyl]sulfanylacetic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1610614-68-0
2-[2-chloro-4-[5-(3,5-dichlorophenyl)-5-(trifluoromethyl)-4H-isothiazol-3-yl]phenyl]sulfanylacetic acid

Guidance literature:: With trifluoroacetic acid; In dichloromethane; at 20 ℃; for 21.5h;

Reference yield:

: 1610614-68-0
2-[2-chloro-4-[5-(3,5-dichlorophenyl)-5-(trifluoromethyl)-4H-isothiazol-3-yl]phenyl]sulfanylacetic acid

: 765-30-0
Cyclopropylamine

: 1610614-20-4
2-[2-chloro-4-[5-(3,5-dichlorophenyl)-5-(trifluoromethyl)-4H-isothiazol-3-yl]phenyl]sulfanyl-N-cyclopropylacetamide

Guidance literature:: With bis-(2-oxo-3-oxazolidinyl)phosphoryl chloride; N-ethyl-N,N-diisopropylamine; at 80 ℃; for 16h;

Reference yield:

: 1610614-68-0
2-[2-chloro-4-[5-(3,5-dichlorophenyl)-5-(trifluoromethyl)-4H-isothiazol-3-yl]phenyl]sulfanylacetic acid

: 1610614-74-8
2-[2-chloro-4-[5-(3,5-dichlorophenyl)-5-(trifluoromethyl)-4H-isothiazol-3-yl]phenyl]sulfanyl-N-cyclopropyl-acetamide

Guidance literature:: Multi-step reaction with 2 steps

1: N-ethyl-N,N-diisopropylamine; bis-(2-oxo-3-oxazolidinyl)phosphoryl chloride / 16 h / 80 °C

2: 3-chloro-benzenecarboperoxoic acid / dichloromethane / 1 h / 0 °C

With bis-(2-oxo-3-oxazolidinyl)phosphoryl chloride; N-ethyl-N,N-diisopropylamine; 3-chloro-benzenecarboperoxoic acid; In dichloromethane;