4,4-dimethyl-2-(3-morpholin-4-yl-phenyl)-1,2,3,4-tetrahydro-quinoline-6-sulfonic acid isopropylamide

Base Information

Chemical Name:4,4-dimethyl-2-(3-morpholin-4-yl-phenyl)-1,2,3,4-tetrahydro-quinoline-6-sulfonic acid isopropylamide
CAS No.:1391609-02-1
Molecular Formula:C₂₄H₃₃N₃O₃S
Molecular Weight:443.61
Hs Code.:

Synonyms:4,4-dimethyl-2-(3-morpholin-4-yl-phenyl)-1,2,3,4-tetrahydro-quinoline-6-sulfonic acid isopropylamide

Suppliers and Price of 4,4-dimethyl-2-(3-morpholin-4-yl-phenyl)-1,2,3,4-tetrahydro-quinoline-6-sulfonic acid isopropylamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 4,4-dimethyl-2-(3-morpholin-4-yl-phenyl)-1,2,3,4-tetrahydro-quinoline-6-sulfonic acid isopropylamide

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 4,4-dimethyl-2-(3-morpholin-4-yl-phenyl)-1,2,3,4-tetrahydro-quinoline-6-sulfonic acid isopropylamide

There total 4 articles about 4,4-dimethyl-2-(3-morpholin-4-yl-phenyl)-1,2,3,4-tetrahydro-quinoline-6-sulfonic acid isopropylamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 40.0%

: 110-91-8,99108-56-2
morpholine

: 1391609-03-2
2-(3-bromo-phenyl)-4,4-dimethyl-1,2,3,4-tetrahydro-quinoline-6-sulfonic acid isopropylamide

: 1391609-02-1
4,4-dimethyl-2-(3-morpholin-4-yl-phenyl)-1,2,3,4-tetrahydro-quinoline-6-sulfonic acid isopropylamide

Guidance literature:: With copper(l) iodide; N,N-dimethylglycine hydrochoride; potassium carbonate; In dimethyl sulfoxide; at 120 ℃; for 16h; Inert atmosphere;

Reference yield:

: 98-74-8
4-Nitrobenzenesulfonyl chloride

: 1391609-02-1
4,4-dimethyl-2-(3-morpholin-4-yl-phenyl)-1,2,3,4-tetrahydro-quinoline-6-sulfonic acid isopropylamide

Guidance literature:: Multi-step reaction with 4 steps

1.1: triethylamine / dichloromethane / 4 h / 20 °C

2.1: ammonium chloride; iron / ethanol; water / 3 h / Reflux

2.2: pH 9

3.1: ytterbium(III) triflate / acetonitrile / 18 h / 80 °C / sealed tube

4.1: potassium carbonate; copper(l) iodide; N,N-dimethylglycine hydrochoride / dimethyl sulfoxide / 16 h / 120 °C / Inert atmosphere

With copper(l) iodide; N,N-dimethylglycine hydrochoride; iron; potassium carbonate; ammonium chloride; triethylamine; ytterbium(III) triflate; In ethanol; dichloromethane; water; dimethyl sulfoxide; acetonitrile;

Reference yield:

: 53668-35-2
sulfanilic acid N-(1-methylethyl) amide

: 1391609-02-1
4,4-dimethyl-2-(3-morpholin-4-yl-phenyl)-1,2,3,4-tetrahydro-quinoline-6-sulfonic acid isopropylamide

Guidance literature:: Multi-step reaction with 2 steps

1: ytterbium(III) triflate / acetonitrile / 18 h / 80 °C / sealed tube

2: potassium carbonate; copper(l) iodide; N,N-dimethylglycine hydrochoride / dimethyl sulfoxide / 16 h / 120 °C / Inert atmosphere

With copper(l) iodide; N,N-dimethylglycine hydrochoride; potassium carbonate; ytterbium(III) triflate; In dimethyl sulfoxide; acetonitrile;