o-Tolyl-dimethylphosphin

Base Information

• Chemical Name: o-Tolyl-dimethylphosphin
• CAS No.: 41845-30-1
• Molecular Formula: C₉H₁₃P
• Molecular Weight: 152.176
• Mol file: 41845-30-1.mol

Synonyms:o-Tolyl-dimethylphosphin

Chemical Property of o-Tolyl-dimethylphosphin

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of o-Tolyl-dimethylphosphin

There total 2 articles about o-Tolyl-dimethylphosphin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

2-methylphenyl bromide (95-46-5) + methyllithium (917-54-4) → o-Tolyl-dimethylphosphin (41845-30-1)

Guidance literature:

2-methylphenyl bromide; With n-butyllithium; zinc(II) chloride; In tetrahydrofuran; hexane; at -78 ℃; for 2.25h; Schlenk technique; Inert atmosphere;

With phosphorus trichloride; In tetrahydrofuran; hexane; at 23 ℃; for 18h; Schlenk technique; Inert atmosphere;

methyllithium; In diethyl ether; at -78 ℃; for 20h; Schlenk technique; Inert atmosphere;

DOI:10.1016/j.jorganchem.2017.04.001

Reference yield:

(2-(methyl)phenyl)dichlorophosphine (5510-87-2) + methyllithium (917-54-4) → o-Tolyl-dimethylphosphin (41845-30-1)

Guidance literature:

In diethyl ether; at -78 - 20 ℃; for 18.4h; Inert atmosphere;

DOI:10.1002/ejic.201301203

Reference yield: 30.5%

o-Tolyl-dimethylphosphin (41845-30-1) + methyl iodide (74-88-4) → I(1-)*C10H16P(1+) (1585177-36-1)

Guidance literature:

at 20 ℃; for 18h; Inert atmosphere; Glovebox;

DOI:10.1002/ejic.201301203

upstream raw materials:

(2-(methyl)phenyl)dichlorophosphine

methyllithium

2-methylphenyl bromide

Downstream raw materials:

I^(1-)*C₁₀H₁₆P⁽¹⁺⁾