ethyl 1-(4-fluorophenyl)-4-((4-fluorophenyl)amino)-5-oxo-2,5-dihydro-1H-pyrrole-3-carboxylate

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Chemical Name:ethyl 1-(4-fluorophenyl)-4-((4-fluorophenyl)amino)-5-oxo-2,5-dihydro-1H-pyrrole-3-carboxylate
CAS No.:1173196-77-4
Molecular Formula:C₁₉H₁₆F₂N₂O₃
Molecular Weight:358.344
Hs Code.:

Synonyms:ethyl 1-(4-fluorophenyl)-4-((4-fluorophenyl)amino)-5-oxo-2,5-dihydro-1H-pyrrole-3-carboxylate

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Chemical Property of ethyl 1-(4-fluorophenyl)-4-((4-fluorophenyl)amino)-5-oxo-2,5-dihydro-1H-pyrrole-3-carboxylate

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Technology Process of ethyl 1-(4-fluorophenyl)-4-((4-fluorophenyl)amino)-5-oxo-2,5-dihydro-1H-pyrrole-3-carboxylate

There total 3 articles about ethyl 1-(4-fluorophenyl)-4-((4-fluorophenyl)amino)-5-oxo-2,5-dihydro-1H-pyrrole-3-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 50-00-0,30525-89-4,61233-19-0
formaldehyd

: 371-40-4
4-fluoroaniline

: 762-21-0
acetylenedicarboxylic acid diethyl ester

: 1173196-77-4
ethyl 1-(4-fluorophenyl)-4-((4-fluorophenyl)amino)-5-oxo-2,5-dihydro-1H-pyrrole-3-carboxylate

Guidance literature:: With glycine; In methanol; at 20 ℃; for 2h; Green chemistry;
DOI:10.1007/s11164-019-04072-z

Reference yield:

: 50-00-0,30525-89-4,61233-19-0
formaldehyd

: 174564-21-7
C₁₄H₁₆FNO₄

: 371-40-4
4-fluoroaniline

: 1173196-77-4
ethyl 1-(4-fluorophenyl)-4-((4-fluorophenyl)amino)-5-oxo-2,5-dihydro-1H-pyrrole-3-carboxylate

Guidance literature:: With iron-doped multi-walled carbon nanotubes; at 20 ℃; for 4.5h; Green chemistry;
DOI:10.1002/aoc.4124

Reference yield:

: 371-40-4
4-fluoroaniline

: 762-21-0
acetylenedicarboxylic acid diethyl ester

: 1173196-77-4
ethyl 1-(4-fluorophenyl)-4-((4-fluorophenyl)amino)-5-oxo-2,5-dihydro-1H-pyrrole-3-carboxylate

Guidance literature:: Multi-step reaction with 2 steps

1: ethanol / 0.33 h / Green chemistry

2: iron‐doped multi‐walled carbon nanotubes / 4.5 h / 20 °C / Green chemistry

With iron-doped multi-walled carbon nanotubes; In ethanol;
DOI:10.1002/aoc.4124