(E)-3-(2-fluorophenyl)-2-methyl-N-(2-(1-methylpyrrolidin-2-yl)ethyl)prop-2-en-1-amine

Base Information

Chemical Name:(E)-3-(2-fluorophenyl)-2-methyl-N-(2-(1-methylpyrrolidin-2-yl)ethyl)prop-2-en-1-amine
CAS No.:1375800-67-1
Molecular Formula:C₁₇H₂₅FN₂
Molecular Weight:276.397
Hs Code.:

Synonyms:(E)-3-(2-fluorophenyl)-2-methyl-N-(2-(1-methylpyrrolidin-2-yl)ethyl)prop-2-en-1-amine

Suppliers and Price of (E)-3-(2-fluorophenyl)-2-methyl-N-(2-(1-methylpyrrolidin-2-yl)ethyl)prop-2-en-1-amine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Matrix Scientific
(E)-3-(2-Fluorophenyl)-2-methyl-N-(2-(1-methyl-pyrrolidin-2-yl)ethyl)prop-2-en-1-amine 97%
5g
$ 1617.00

Total 1 raw suppliers

Chemical Property of (E)-3-(2-fluorophenyl)-2-methyl-N-(2-(1-methylpyrrolidin-2-yl)ethyl)prop-2-en-1-amine

Chemical Property:

Purity/Quality:

95%-98% ^*data from raw suppliers

(E)-3-(2-Fluorophenyl)-2-methyl-N-(2-(1-methyl-pyrrolidin-2-yl)ethyl)prop-2-en-1-amine 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (E)-3-(2-fluorophenyl)-2-methyl-N-(2-(1-methylpyrrolidin-2-yl)ethyl)prop-2-en-1-amine

There total 4 articles about (E)-3-(2-fluorophenyl)-2-methyl-N-(2-(1-methylpyrrolidin-2-yl)ethyl)prop-2-en-1-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: C₁₇H₂₃FN₂

: 1375800-67-1
(E)-3-(2-fluorophenyl)-2-methyl-N-(2-(1-methylpyrrolidin-2-yl)ethyl)prop-2-en-1-amine

Guidance literature:: C₁₇H₂₃FN₂; With sodium tetrahydroborate; In methanol; at 0 ℃; for 1h; Inert atmosphere;

With acetone; In methanol; at 20 ℃; for 0.166667h;

With water; potassium carbonate; In dichloromethane; pH=> 10;
DOI:10.1016/j.ejmech.2012.02.041

Reference yield:

: 446-52-6
2-Fluorobenzaldehyde

: 1375800-67-1
(E)-3-(2-fluorophenyl)-2-methyl-N-(2-(1-methylpyrrolidin-2-yl)ethyl)prop-2-en-1-amine

Guidance literature:: Multi-step reaction with 3 steps

1.1: potassium hydroxide / ethanol; water / 0 - 20 °C / Inert atmosphere

2.1: sodium sulfate / dichloromethane / 24 h / 20 °C / Inert atmosphere

3.1: sodium tetrahydroborate / methanol / 1 h / 0 °C / Inert atmosphere

3.2: 0.17 h / 20 °C

3.3: pH > 10

With sodium tetrahydroborate; sodium sulfate; potassium hydroxide; In methanol; ethanol; dichloromethane; water;
DOI:10.1016/j.ejmech.2012.02.041

Reference yield:

: 51387-90-7,422545-96-8
2-(2-AMINOETHYL)-1-METHYLPYRROLIDINE

: 1375800-67-1
(E)-3-(2-fluorophenyl)-2-methyl-N-(2-(1-methylpyrrolidin-2-yl)ethyl)prop-2-en-1-amine

Guidance literature:: Multi-step reaction with 2 steps

1.1: sodium sulfate / dichloromethane / 24 h / 20 °C / Inert atmosphere

2.1: sodium tetrahydroborate / methanol / 1 h / 0 °C / Inert atmosphere

2.2: 0.17 h / 20 °C

2.3: pH > 10

With sodium tetrahydroborate; sodium sulfate; In methanol; dichloromethane;
DOI:10.1016/j.ejmech.2012.02.041