2-(2-bromobenzyl)-2-[4-(dimethylamino)phenyl]-1,3-dithiane

Base Information

• Chemical Name: 2-(2-bromobenzyl)-2-[4-(dimethylamino)phenyl]-1,3-dithiane
• CAS No.: 1127955-61-6
• Molecular Formula: C₁₉H₂₂BrNS₂
• Molecular Weight: 408.426
• Mol file: 1127955-61-6.mol

Synonyms:2-(2-bromobenzyl)-2-[4-(dimethylamino)phenyl]-1,3-dithiane

Chemical Property of 2-(2-bromobenzyl)-2-[4-(dimethylamino)phenyl]-1,3-dithiane

Chemical Property:

Purity/Quality:

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Technology Process of 2-(2-bromobenzyl)-2-[4-(dimethylamino)phenyl]-1,3-dithiane

There total 1 articles about 2-(2-bromobenzyl)-2-[4-(dimethylamino)phenyl]-1,3-dithiane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 45.0%

4-(N,N'-dimethylamino)phenyl-1,3-dithiane (24588-75-8) + 1-Bromo-2-bromomethyl-benzene (3433-80-5) → 2-(2-bromobenzyl)-2-[4-(dimethylamino)phenyl]-1,3-dithiane (1127955-61-6)

Guidance literature:

4-(N,N'-dimethylamino)phenyl-1,3-dithiane; With n-butyllithium; In tetrahydrofuran; hexane; at -50 ℃; Inert atmosphere;

1-Bromo-2-bromomethyl-benzene; In tetrahydrofuran; hexane;

DOI:10.1055/s-0028-1083261

Reference yield: 40.0%

2-(2-bromobenzyl)-2-[4-(dimethylamino)phenyl]-1,3-dithiane (1127955-61-6) → 2-bromobenzyl 4-(dimethylamino)phenyl ketone (1127955-74-1)

Guidance literature:

With mercury(II) diacetate; water; In acetonitrile; at 20 ℃; for 0.416667h;

DOI:10.1055/s-0028-1083261

upstream raw materials:

4-(N,N'-dimethylamino)phenyl-1,3-dithiane

1-Bromo-2-bromomethyl-benzene

Downstream raw materials:

2-bromobenzyl 4-(dimethylamino)phenyl ketone