C₁₅H₁₄F₃NO₂

Base Information

Chemical Name:C₁₅H₁₄F₃NO₂
CAS No.:1365321-45-4
Molecular Formula:C₁₅H₁₄F₃NO₂
Molecular Weight:297.277
Hs Code.:

C<sub>15</sub>H<sub>14</sub>F<sub>3</sub>NO<sub>2</sub>

Synonyms:C₁₅H₁₄F₃NO₂

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of C₁₅H₁₄F₃NO₂

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Technology Process of C₁₅H₁₄F₃NO₂

There total 2 articles about C₁₅H₁₄F₃NO₂ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: C₁₅H₁₂F₃NO₂

: 1365321-45-4
C₁₅H₁₄F₃NO₂

Guidance literature:: With methanol; sodium tetrahydroborate; In water; dimethyl sulfoxide; at 0 ℃; for 0.5h;
DOI:10.1016/j.tet.2012.01.095

Reference yield:

: 17533-08-3
1-iodo-2,4,5-trifluorobenzene

: 1365321-45-4
C₁₅H₁₄F₃NO₂

Guidance literature:: Multi-step reaction with 3 steps

1: N-benzyl-N,N,N-triethylammonium chloride; palladium diacetate; sodium hydrogencarbonate / N,N-dimethyl-formamide / 20 h / 45 °C / Inert atmosphere

2: L-proline / water; dimethyl sulfoxide / 0.5 h / 30 °C

3: methanol; sodium tetrahydroborate / water; dimethyl sulfoxide / 0.5 h / 0 °C

With methanol; sodium tetrahydroborate; N-benzyl-N,N,N-triethylammonium chloride; palladium diacetate; sodium hydrogencarbonate; L-proline; In water; dimethyl sulfoxide; N,N-dimethyl-formamide; 1: Heck reaction;
DOI:10.1016/j.tet.2012.01.095