meso-3,4-diphenyladipic acid dimethyl ester

Base Information

• Chemical Name: meso-3,4-diphenyladipic acid dimethyl ester
• CAS No.: 7028-47-9
• Molecular Formula: C₂₀H₂₂O₄
• Molecular Weight: 326.392
• Mol file: 7028-47-9.mol

Synonyms:meso-3,4-diphenyladipic acid dimethyl ester

Chemical Property of meso-3,4-diphenyladipic acid dimethyl ester

Chemical Property:

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of meso-3,4-diphenyladipic acid dimethyl ester

There total 51 articles about meso-3,4-diphenyladipic acid dimethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

methyl cinnamate (103-26-4,1754-62-7) → meso-3,4-diphenyladipic acid dimethyl ester (7028-47-9)

Guidance literature:

With samarium diiodide; C₇H₂₀N₃O₂P; In tetrahydrofuran; Glovebox; Inert atmosphere;

DOI:10.1021/jo500161s

Reference yield: 80.0%

methyl cinnamate (103-26-4,1754-62-7) → 3-phenylpropanoic acid methyl ester (103-25-3) + meso-3,4-diphenyladipic acid dimethyl ester (7028-47-9)

Guidance literature:

With methanol; N,N,N,N,N,N-hexamethylphosphoric triamide; samarium diiodide; In tetrahydrofuran; Inert atmosphere;

DOI:10.1021/jo500161s

Reference yield: 67.0%

benzophenone (119-61-9) + 1-Methoxy-1-(tert-butyldimethylsiloxy)-2-phenylcyclopropane → tetraphenylethane-1,2-diol (464-72-2) + meso-3,4-diphenyladipic acid dimethyl ester (7028-47-9) + 4,5,5-triphenyldihydrofuran-2(3H)-one (57697-68-4) + Methyl 4-hydroxy-3,4,4-triphenylbutanoate

Guidance literature:

With magnesium(II) perchlorate; water; In acetonitrile; for 10h; Product distribution; Mechanism; Ambient temperature; Irradiation; other times, temperature; also under anhydrous conditions in the presence or absence of naphthalene; also for other cyclopropanone acetals and carbonyl compounds;

DOI:10.1021/jo00115a022

upstream raw materials:

methyl (2Z)-3-phenylprop-2-enoate

benzoyl cyanide

2-acetylpyridine

benzophenone

Downstream raw materials:

trans-3,4-diphenylcyclopentanone

(+/-)-3,4-diphenylhexane-1,6-diol

racem.-3,4-diphenyl-adipic acid

trans-1,2-diphenylcyclopentane