(Z)-3-(4-methoxyphenyl)-2-(4-nitrophenyl)prop-2-enenitrile

Base Information

• Chemical Name: (Z)-3-(4-methoxyphenyl)-2-(4-nitrophenyl)prop-2-enenitrile
• CAS No.: 6582-07-6
• Molecular Formula: C₁₆H₁₂N₂O₃
• Molecular Weight: 280.283
• European Community (EC) Number: 665-775-5
• Nikkaji Number: J800.613J
• ChEMBL ID: CHEMBL3134410

Synonyms:CHEMBL3134410;(Z)-3-(4-methoxyphenyl)-2-(4-nitrophenyl)prop-2-enenitrile;6582-07-6;3-(4-methoxyphenyl)-2-(4-nitrophenyl)acrylonitrile;SCHEMBL10389445;HMS557C08;FJBBWHCHJAMHGD-GXDHUFHOSA-N;BDBM50496612;AKOS001013756;4-METHOXY-ALPHA-(4-NITROPHENYL)CINNAMONITRILE;Z44301966;Benzeneacetonitrile, .alpha.-[(4-methoxyphenyl)methylidene]-4-nitro-

Chemical Property of (Z)-3-(4-methoxyphenyl)-2-(4-nitrophenyl)prop-2-enenitrile

Chemical Property:

• XLogP3: 3.5
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 3
• Exact Mass: 280.08479225
• Heavy Atom Count: 21
• Complexity: 430

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: COC1=CC=C(C=C1)C=C(C#N)C2=CC=C(C=C2)[N+](=O)[O-]
• Isomeric SMILES: COC1=CC=C(C=C1)/C=C(\C#N)/C2=CC=C(C=C2)[N+](=O)[O-]

Technology Process of (Z)-3-(4-methoxyphenyl)-2-(4-nitrophenyl)prop-2-enenitrile

There total 3 articles about (Z)-3-(4-methoxyphenyl)-2-(4-nitrophenyl)prop-2-enenitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 45.0%

diethyl-2-(4-methoxybenzylidene)malonate (6768-23-6) + 4-Nitrophenylacetonitrile (555-21-5,34512-13-5,174848-08-9) → 3-(4-methoxy-phenyl)-2-(4-nitro-phenyl)-acrylonitrile (6582-07-6)

Guidance literature:

With sodium methylate; In methanol; at 20 ℃;

DOI:10.1021/jo802241x

Reference yield:

4-Nitrophenylacetonitrile (555-21-5,34512-13-5,174848-08-9) + 4-methoxy-benzaldehyde (123-11-5) → 3-(4-methoxy-phenyl)-2-(4-nitro-phenyl)-acrylonitrile (6582-07-6)

Guidance literature:

With sodium ethanolate;

Reference yield:

→ 3-(4-methoxy-phenyl)-2-(4-nitro-phenyl)-acrylonitrile (6582-07-6)

Guidance literature:

p-Methoxybenzaldehyd, p-Nitrophenylacetonitril;

DOI:10.1021/je60045a005

upstream raw materials:

4-Nitrophenylacetonitrile

4-methoxy-benzaldehyde

diethyl-2-(4-methoxybenzylidene)malonate

Downstream raw materials:

2-(4-amino-phenyl)-3-(4-methoxy-phenyl)-acrylonitrile

(2R,3S)-3-(4-Methoxy-phenyl)-2-(4-nitro-phenyl)-oxirane-2-carbonitrile

3-(4-methoxyphenyl)-2-(4-nitrophenyl)propanenitrile

2-Cyano-5-(p-methoxyphenyl)-2-(p-nitrophenyl)tetrahydrofuran-3,4-dicarboxylic anhydride

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 6582-07-6 3-(4-methoxy-phenyl)-2-(4-nitro-phenyl)-acrylonitrile

Send

Send

Metric Ton KG G Pound L ML

Send

Send