(R,S)-2-(amino(4-fluorophenyl)methyl)-N-(5-methyl-1H-pyrazol-3-yl)quinazolin-4-amine acetate

Base Information

Chemical Name:(R,S)-2-(amino(4-fluorophenyl)methyl)-N-(5-methyl-1H-pyrazol-3-yl)quinazolin-4-amine acetate
CAS No.:1360652-11-4
Molecular Formula:C₂H₄O₂*C₁₉H₁₇FN₆
Molecular Weight:408.435
Hs Code.:

Synonyms:(R,S)-2-(amino(4-fluorophenyl)methyl)-N-(5-methyl-1H-pyrazol-3-yl)quinazolin-4-amine acetate

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Chemical Property of (R,S)-2-(amino(4-fluorophenyl)methyl)-N-(5-methyl-1H-pyrazol-3-yl)quinazolin-4-amine acetate

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Technology Process of (R,S)-2-(amino(4-fluorophenyl)methyl)-N-(5-methyl-1H-pyrazol-3-yl)quinazolin-4-amine acetate

There total 1 articles about (R,S)-2-(amino(4-fluorophenyl)methyl)-N-(5-methyl-1H-pyrazol-3-yl)quinazolin-4-amine acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 9.0%

: 31230-17-8
3-methyl-5-aminopyrazole

: 1241914-95-3
(R,S)-2-((benzyloxycarbonylamino)(4-fluorophenyl)methyl)-quinazolin-4-yl-2,4,6-triisopropylbenzenesulfonate

: 64-19-7,77671-22-8
acetic acid

: 1360652-11-4
(R,S)-2-(amino(4-fluorophenyl)methyl)-N-(5-methyl-1H-pyrazol-3-yl)quinazolin-4-amine acetate

Guidance literature:: 3-methyl-5-aminopyrazole; (R,S)-2-((benzyloxycarbonylamino)(4-fluorophenyl)methyl)-quinazolin-4-yl-2,4,6-triisopropylbenzenesulfonate; With potassium iodide; In ISOPROPYLAMIDE; at 55 ℃; for 4h;

With hydrogen; 10% Pd(OH)2/C; In methanol; for 6h;

acetic acid; In water; acetonitrile;