(S)-2-<oxy>-6-<<(phenylmethoxy)carbonyl>amino>hexanoic acid

Base Information

• Chemical Name: (S)-2-<oxy>-6-<<(phenylmethoxy)carbonyl>amino>hexanoic acid
• CAS No.: 107492-16-0
• Molecular Formula: C₂₄H₃₂NO₇P
• Molecular Weight: 477.494

Synonyms:(S)-2-<oxy>-6-<<(phenylmethoxy)carbonyl>amino>hexanoic acid

Chemical Property of (S)-2-<oxy>-6-<<(phenylmethoxy)carbonyl>amino>hexanoic acid

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of (S)-2-<oxy>-6-<<(phenylmethoxy)carbonyl>amino>hexanoic acid

There total 7 articles about (S)-2-<oxy>-6-<<(phenylmethoxy)carbonyl>amino>hexanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

(S)-6-Benzyloxycarbonylamino-2-[hydroxy-(4-phenyl-butyl)-phosphinoyloxy]-hexanoic acid methyl ester (107492-15-9) → (S)-2-<oxy>-6-<<(phenylmethoxy)carbonyl>amino>hexanoic acid (107492-16-0)

Guidance literature:

With sodium hydroxide; In 1,4-dioxane; for 2h; Ambient temperature;

DOI:10.1021/jm00167a028

Reference yield:

(S)-2-[[Hydroxy(4-phenylbutyl)phosphinyl]oxy]-6-[[(phenylmethoxy)carbonyl]amino]hexanoic acid, methyl ester → (S)-2-<oxy>-6-<<(phenylmethoxy)carbonyl>amino>hexanoic acid (107492-16-0)

Guidance literature:

With sodium hydroxide; In 1,4-dioxane;

Reference yield:

(4-phenylbutyl)phosphinic acid (86552-32-1) → (S)-2-<oxy>-6-<<(phenylmethoxy)carbonyl>amino>hexanoic acid (107492-16-0)

Guidance literature:

Multi-step reaction with 3 steps

1: 5.77 g / N,N'-dicyclohexylcarbodiimide, 4-(dimethylamino)pyridine / tetrahydrofuran / 0.67 h / Ambient temperature

2: NaIO₄ / dioxane; H₂O / 16 h / Ambient temperature

3: 99 percent / 2.0 N NaOH / dioxane / 2 h / Ambient temperature

With dmap; sodium hydroxide; sodium periodate; dicyclohexyl-carbodiimide; In tetrahydrofuran; 1,4-dioxane; water;

DOI:10.1021/jm00167a028

upstream raw materials:

{4-[(S)-2,5-Dioxo-2-(4-phenyl-butyl)-2λ⁵-[1,3,2]dioxaphospholan-4-yl]-butyl}-carbamic acid benzyl ester

(S)-6-Benzyloxycarbonylamino-2-[hydroxy-(4-phenyl-butyl)-phosphinoyloxy]-hexanoic acid methyl ester

(4-phenylbutyl)phosphinic acid

(S)-6-[[(Phenylmethoxy)carbonyl]amino]-2-hydroxyhexanoic acid

Downstream raw materials:

(S)-oxy>-1-oxo-6-<<(phenylmethoxy)carbonyl>amino>hexyl>amino>acetic acid phenylmethyl ester

({(S)-6-Benzyloxycarbonylamino-2-[hydroxy-(4-phenyl-butyl)-phosphinoyloxy]-hexanoyl}-indan-2-yl-amino)-acetic acid benzyl ester

{4-[(S)-2,5-Dioxo-2-(4-phenyl-butyl)-2λ⁵-[1,3,2]dioxaphospholan-4-yl]-butyl}-carbamic acid benzyl ester

ceronapril

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 107492-16-0 (S)-2-<oxy>-6-<<(phenylmethoxy)carbonyl>amino>hexanoic acid

Send

Send

Metric Ton KG G Pound L ML

Send

Send