benzyl 3α,7α,12α-trihydroxyl-5β-cholestane-24-carboxylic ester

Base Information

• Chemical Name: benzyl 3α,7α,12α-trihydroxyl-5β-cholestane-24-carboxylic ester
• CAS No.: 105730-97-0
• Molecular Formula: C₃₁H₄₆O₅
• Molecular Weight: 498.703
• Mol file: 105730-97-0.mol

Synonyms:benzyl 3α,7α,12α-trihydroxyl-5β-cholestane-24-carboxylic ester

Chemical Property of benzyl 3α,7α,12α-trihydroxyl-5β-cholestane-24-carboxylic ester

Chemical Property:

Purity/Quality:

Safty Information:

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• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of benzyl 3α,7α,12α-trihydroxyl-5β-cholestane-24-carboxylic ester

There total 4 articles about benzyl 3α,7α,12α-trihydroxyl-5β-cholestane-24-carboxylic ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

cholic acid (81-25-4) + benzyl bromide (100-39-0) → benzyl 3α,7α,12α-trihydroxyl-5β-cholestane-24-carboxylic ester (105730-97-0)

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide; at 0 - 25 ℃; for 12h;

DOI:10.1021/acs.jmedchem.8b01357

Reference yield: 89.0%

cholic acid (81-25-4) + benzyl alcohol (100-51-6,185532-71-2) → benzyl 3α,7α,12α-trihydroxyl-5β-cholestane-24-carboxylic ester (105730-97-0)

Guidance literature:

With toluene-4-sulfonic acid; sodium sulfate; In 1,4-dioxane; for 0.166667h; microwave irradiation;

DOI:10.1016/j.steroids.2004.09.007

Reference yield: 81.0%

cholic acid (81-25-4) → benzyl 3α,7α,12α-trihydroxyl-5β-cholestane-24-carboxylic ester (105730-97-0)

Guidance literature:

In methanol; dichloromethane; benzyl alcohol;

upstream raw materials:

cholic acid

benzyl bromide

benzyl alcohol

Downstream raw materials:

(R)-4-[(3R,5S,7R,8R,9S,10S,12S,13R,14S,17R)-3,7,12-Tris-(2-tert-butoxycarbonylamino-acetoxy)-10,13-dimethyl-hexadecahydro-cyclopenta[a]phenanthren-17-yl]-pentanoic acid benzyl ester

(R)-4-[(3R,5S,7R,8R,9S,10S,12S,13R,14S,17R)-3,7,12-Tris-(3-tert-butoxycarbonylamino-propionyloxy)-10,13-dimethyl-hexadecahydro-cyclopenta[a]phenanthren-17-yl]-pentanoic acid benzyl ester

Benzyl 3-O-[bis(2-chloroethyl)aminocarbonyl] cholate

benzyl 3α-isonicotinoyloxy-7α,12α-dihydroxycholanate