2-Chloro-5-nitroquinoline

Base Information

Chemical Name:2-Chloro-5-nitroquinoline
CAS No.:13067-94-2
Molecular Formula:C9H5ClN2O2
Molecular Weight:208.604
Hs Code.:2933499090
NSC Number:261562
DSSTox Substance ID:DTXSID60312772
Wikidata:Q82063499
ChEMBL ID:CHEMBL2042582
Mol file:13067-94-2.mol

Synonyms:Quinoline, 2-chloro-5-nitro-;2-chloro-5-nitroquinoline;

Suppliers and Price of 2-Chloro-5-nitroquinoline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-Chloro-5-nitroquinoline
500mg
$ 165.00

TRC
2-Chloro-5-nitroquinoline
5g
$ 1320.00

Medical Isotopes, Inc.
2-Chloro-5-nitroquinoline
5 g
$ 2200.00

Crysdot
2-Chloro-5-nitroquinoline 98%
5g
$ 297.00

Crysdot
2-Chloro-5-nitroquinoline 98%
1g
$ 99.00

Chemenu
2-Chloro-5-nitroquinoline 98%
5g
$ 281.00

Chemenu
2-Chloro-5-nitroquinoline 98%
1g
$ 102.00

American Custom Chemicals Corporation
2-CHLORO-5-NITROQUINOLINE 95.00%
5MG
$ 496.88

Alichem
2-Chloro-5-nitroquinoline
5g
$ 294.00

Total 19 raw suppliers

Chemical Property of 2-Chloro-5-nitroquinoline

Chemical Property:

Vapor Pressure:8.18E-05mmHg at 25°C
Boiling Point:351.7°Cat760mmHg
Flash Point:166.5°C
PSA：58.71000
Density:1.484g/cm³
LogP:3.31960
Storage Temp.:under inert gas (nitrogen or Argon) at 2-8°C
Solubility.:Methanol, Ethyl Acetate
XLogP3:2.8
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:0
Exact Mass:208.0039551
Heavy Atom Count:14
Complexity:231

Purity/Quality:

97% ^*data from raw suppliers

2-Chloro-5-nitroquinoline ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC2=C(C=CC(=N2)Cl)C(=C1)[N+](=O)[O-]
Uses 2-Chloro-5-nitroquinoline is used in the synthesis of potent, orally active corticotropin-releasing factor-1 receptor antagonists.

Technology Process of 2-Chloro-5-nitroquinoline

There total 9 articles about 2-Chloro-5-nitroquinoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

: 6938-27-8
5-nitro-2<1H>quinolinone

: 13067-94-2
2-chloro-5-nitroquinoline

Guidance literature:: With trichlorophosphate; In 1,2-dichloro-ethane; at 80 ℃; for 12h;
DOI:10.1016/j.ejmech.2018.03.023

Reference yield: 54.0%

: 612-62-4
2-Chloroquinoline

: 13067-94-2
2-chloro-5-nitroquinoline

: 4225-86-9
2-chloro-8-nitroquinoline

Guidance literature:: 2-Chloroquinoline; With sulfuric acid; nitric acid; at 0 - 20 ℃; for 1h;

With sodium carbonate; In water;
DOI:10.1016/j.ejmech.2012.04.029

Reference yield: 46.0%

: 7613-19-6
5-nitro-quinoline-1-oxide

: 13067-94-2
2-chloro-5-nitroquinoline

Guidance literature:: With trichloroacetonitrile; triphenylphosphine; In toluene; at 115 ℃; for 4h; regioselective reaction; Sealed tube;
DOI:10.1002/ejoc.201501567