6-chloro-2-(4-nitrobenzenesulfonyl)-1-vinyl-2,3,4,9-tetrahydro-1H-β-carboline

Base Information

Chemical Name:6-chloro-2-(4-nitrobenzenesulfonyl)-1-vinyl-2,3,4,9-tetrahydro-1H-β-carboline
CAS No.:859163-72-7
Molecular Formula:C₁₉H₁₆ClN₃O₄S
Molecular Weight:417.873
Hs Code.:

Synonyms:6-chloro-2-(4-nitrobenzenesulfonyl)-1-vinyl-2,3,4,9-tetrahydro-1H-β-carboline

Suppliers and Price of 6-chloro-2-(4-nitrobenzenesulfonyl)-1-vinyl-2,3,4,9-tetrahydro-1H-β-carboline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 6-chloro-2-(4-nitrobenzenesulfonyl)-1-vinyl-2,3,4,9-tetrahydro-1H-β-carboline

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 6-chloro-2-(4-nitrobenzenesulfonyl)-1-vinyl-2,3,4,9-tetrahydro-1H-β-carboline

There total 5 articles about 6-chloro-2-(4-nitrobenzenesulfonyl)-1-vinyl-2,3,4,9-tetrahydro-1H-β-carboline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 859163-71-6
N-(1-benzyloxyallyl)-N-[2-(5-chloro-1H-indol-3-yl)ethyl]-4-nitrobenzenesulfonylamide

: 859163-72-7
6-chloro-2-(4-nitrobenzenesulfonyl)-1-vinyl-2,3,4,9-tetrahydro-1H-β-carboline

Guidance literature:: With tin(II) trifluoromethanesulfonate; In dichloromethane; at 0 ℃; for 2h;
DOI:10.1021/jo050503t

Reference yield:

: 98993-95-4
5-chloro-3-(2-nitrovinyl)indole

: 859163-72-7
6-chloro-2-(4-nitrobenzenesulfonyl)-1-vinyl-2,3,4,9-tetrahydro-1H-β-carboline

Guidance literature:: Multi-step reaction with 4 steps

1: 99 percent / LiAlH₄ / tetrahydrofuran / 2 h / Heating

2: 75 percent / Et₃N / CH₂Cl₂ / 6 h / 20 °C

3: 83 percent / Et₃N / Pd(OAc)2 / acetonitrile / 2 h / 20 °C

4: 94 percent / Sn(OTf)2 / CH₂Cl₂ / 2 h / 0 °C

With lithium aluminium tetrahydride; tin(II) trifluoromethanesulfonate; triethylamine; palladium diacetate; In tetrahydrofuran; dichloromethane; acetonitrile;
DOI:10.1021/jo050503t

Reference yield:

: 859163-70-5
N-[2-(5-chloro-1H-indol-3-yl)ethyl]-4-nitrobenzenesulfonylamide

: 859163-72-7
6-chloro-2-(4-nitrobenzenesulfonyl)-1-vinyl-2,3,4,9-tetrahydro-1H-β-carboline

Guidance literature:: Multi-step reaction with 2 steps

1: 83 percent / Et₃N / Pd(OAc)2 / acetonitrile / 2 h / 20 °C

2: 94 percent / Sn(OTf)2 / CH₂Cl₂ / 2 h / 0 °C

With tin(II) trifluoromethanesulfonate; triethylamine; palladium diacetate; In dichloromethane; acetonitrile;
DOI:10.1021/jo050503t