1-benzylimidazole-2-carboxylic acid hydrochloride

Base Information

Chemical Name:1-benzylimidazole-2-carboxylic acid hydrochloride
CAS No.:123566-30-3
Molecular Formula:C₁₁H₁₀N₂O₂*ClH
Molecular Weight:238.674
Hs Code.:

Synonyms:1-benzylimidazole-2-carboxylic acid hydrochloride

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 1-benzylimidazole-2-carboxylic acid hydrochloride

Chemical Property:

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Technology Process of 1-benzylimidazole-2-carboxylic acid hydrochloride

There total 3 articles about 1-benzylimidazole-2-carboxylic acid hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 40.0%

: 4238-71-5
1-benzylimidazole

: 124-38-9,18923-20-1
carbon dioxide

: 123566-30-3
1-benzylimidazole-2-carboxylic acid hydrochloride

Guidance literature:: 1-benzylimidazole; With n-butyllithium; In hexanes; diethyl ether; at -50 ℃; Inert atmosphere;

carbon dioxide; In hexanes; diethyl ether; at 25 ℃;

With hydrogenchloride; In water; pH=3;

Reference yield:

: 16042-26-5
1-(phenylmethyl)-1H-imidazole-2-carboxylic acid

: 123566-30-3
1-benzylimidazole-2-carboxylic acid hydrochloride

Guidance literature:: With hydrogenchloride; In methanol; diethyl ether;

Reference yield:

: 4238-71-5
1-benzylimidazole

: 123566-30-3
1-benzylimidazole-2-carboxylic acid hydrochloride

Guidance literature:: Multi-step reaction with 2 steps

1.1: n-butyllithium / diethyl ether; hexanes / 0.33 h / -50 °C / Inert atmosphere

1.2: -50 - 25 °C

1.3: pH 3 / Acidic conditions

2.1: hydrogenchloride / diethyl ether; methanol

With hydrogenchloride; n-butyllithium; In methanol; hexanes; diethyl ether;