3-isoadenosine

Base Information

Chemical Name:3-isoadenosine
CAS No.:2273-78-1
Molecular Formula:C10H13 N5 O4
Molecular Weight:267.244
Hs Code.:
Mol file:2273-78-1.mol

Synonyms:Adenine,3-b-D-ribofuranosyl- (7CI,8CI);3-Isoadenosine; 3-b-D-Ribofuranosyladenine; 6-Amino-3-b-D-ribofuranosylpurine; NSC 82825

Suppliers and Price of 3-isoadenosine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 9 raw suppliers

Chemical Property of 3-isoadenosine

Chemical Property:

Vapor Pressure:2.04E-13mmHg at 25°C
Boiling Point:529.4°C at 760 mmHg
PKA:12.84±0.70(Predicted)
Flash Point:274°C
PSA：139.54000
Density:2.08g/cm³
LogP:-1.39880

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 3-isoadenosine

There total 4 articles about 3-isoadenosine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1,2-anhydro-5-O-trityl-α-D-ribofuranose

: 66224-66-6,66224-67-7,66224-68-8,66224-69-9,134434-48-3,134434-49-4,134454-76-5,134461-75-9
adenine

: 2273-78-1
3-[beta-D-Ribofuranosyl]-adenine

: 58-61-7
adenosine

Guidance literature:: adenine; With sodium hydride; In N,N-dimethyl-formamide; mineral oil; at 20 ℃; for 0.25h; Inert atmosphere;

1,2-anhydro-5-O-trityl-α-D-ribofuranose; In N,N-dimethyl-formamide; mineral oil; at 20 ℃; for 12h; Inert atmosphere;

With trifluoroacetic acid; In water; at 0 - 20 ℃; for 12h; Overall yield = 451 mg; Inert atmosphere;
DOI:10.1002/chem.201604955

Reference yield:

: 55726-00-6,72521-12-1,72521-13-2,72521-20-1,72521-21-2,72521-22-3,131285-09-1,131285-24-0
(3R,4S,5R)-5-((trityloxy)methyl)tetrahydrofuran-2,3,4-triol

: 2273-78-1
3-[beta-D-Ribofuranosyl]-adenine

: 58-61-7
adenosine

Guidance literature:: Multi-step reaction with 2 steps

1.1: tributylphosphine; 1,1'-azodicarbonyl-dipiperidine / acetonitrile / 0.25 h / 20 °C / Inert atmosphere

2.1: sodium hydride / N,N-dimethyl-formamide; mineral oil / 0.25 h / 20 °C / Inert atmosphere

2.2: 12 h / 20 °C / Inert atmosphere

2.3: 12 h / 0 - 20 °C / Inert atmosphere

With tributylphosphine; sodium hydride; 1,1'-azodicarbonyl-dipiperidine; In N,N-dimethyl-formamide; acetonitrile; mineral oil;
DOI:10.1002/chem.201604955

Reference yield:

: 41028-66-4
1,5-anhydroribitol

: 2273-78-1
3-[beta-D-Ribofuranosyl]-adenine

: 58-61-7
adenosine

Guidance literature:: Multi-step reaction with 3 steps

1.1: pyridine / 6 h / 50 °C / Inert atmosphere

2.1: tributylphosphine; 1,1'-azodicarbonyl-dipiperidine / acetonitrile / 0.25 h / 20 °C / Inert atmosphere

3.1: sodium hydride / N,N-dimethyl-formamide; mineral oil / 0.25 h / 20 °C / Inert atmosphere

3.2: 12 h / 20 °C / Inert atmosphere

3.3: 12 h / 0 - 20 °C / Inert atmosphere

With pyridine; tributylphosphine; sodium hydride; 1,1'-azodicarbonyl-dipiperidine; In N,N-dimethyl-formamide; acetonitrile; mineral oil;
DOI:10.1002/chem.201604955