3'-azidothymidine 5'-[p-methoxyphenyl methoxyalaninyl phosphate]

Base Information

• Chemical Name: 3'-azidothymidine 5'-[p-methoxyphenyl methoxyalaninyl phosphate]
• CAS No.: 149560-32-7
• Molecular Formula: C₂₁H₂₇N₆O₉P
• Molecular Weight: 538.454

Synonyms:3'-azidothymidine 5'-[p-methoxyphenyl methoxyalaninyl phosphate]

Chemical Property of 3'-azidothymidine 5'-[p-methoxyphenyl methoxyalaninyl phosphate]

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3'-azidothymidine 5'-[p-methoxyphenyl methoxyalaninyl phosphate]

There total 7 articles about 3'-azidothymidine 5'-[p-methoxyphenyl methoxyalaninyl phosphate] which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

3'-azido-2',3'-deoxythymidine (30516-87-1,399024-19-2) + (4‐methoxy)phenyl (methoxy‐L‐alaninyl)phosphorochloridate (147907-38-8) → 3'-azidothymidine 5'-[p-methoxyphenyl methoxyalaninyl phosphate] (149560-32-7)

Guidance literature:

With 1-methyl-1H-imidazole; In tetrahydrofuran; for 16h; Ambient temperature;

DOI:10.1021/jm00060a013

Reference yield:

(4‐methoxy)phenyl (methoxy‐L‐alaninyl)phosphorochloridate (147907-38-8) + 3'-azido-3'-deoxythymidine-5'-methoxyalaninyl phosphate (209214-06-2) → C21H27N6O9P + 3'-azidothymidine 5'-[p-methoxyphenyl methoxyalaninyl phosphate] (149560-32-7)

Guidance literature:

With 1-methyl-1H-imidazole;

Reference yield:

C17H20N5O7P (879688-27-4) + L-Alanine methyl ester (10065-72-2) → 3'-azidothymidine 5'-[p-methoxyphenyl methoxyalaninyl phosphate] (149560-32-7)

Guidance literature:

With N-chloro-succinimide; triethylamine; In dichloromethane; at 20 ℃; for 2h;

DOI:10.1055/s-2005-917085

upstream raw materials:

3'-azido-2',3'-deoxythymidine

(4‐methoxy)phenyl (methoxy‐L‐alaninyl)phosphorochloridate

C₁₇H₂₀N₅O₇P

L-Alanine methyl ester

Downstream raw materials:

4-methoxy-phenol

2(S)-(3-deoxy-3-azidothymidyl(hydroxy)phosphorylamino)propionic acid methyl ester

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 149560-32-7 3'-azidothymidine 5'-[p-methoxyphenyl methoxyalaninyl phosphate]

Send

Send

Metric Ton KG G Pound L ML

Send

Send