4,7beta-Dimethyl-4-azacholestan-3-one

Base Information

Chemical Name:4,7beta-Dimethyl-4-azacholestan-3-one
CAS No.:158493-17-5
Molecular Formula:C₂₈H₄₉NO
Molecular Weight:415.703
Hs Code.:
UNII:JWDKP12EUC
DSSTox Substance ID:DTXSID20935926
Nikkaji Number:J890.706D
Wikipedia:MK-386
Mol file:158493-17-5.mol

Synonyms:4,7beta-dimethyl-4-azacholestan-3-one;MK 386;MK-386

Suppliers and Price of 4,7beta-Dimethyl-4-azacholestan-3-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 4,7beta-Dimethyl-4-azacholestan-3-one

Chemical Property:

Vapor Pressure:2.48E-10mmHg at 25°C
Boiling Point:505.2°Cat760mmHg
Flash Point:203.9°C
Density:0.951g/cm³
XLogP3:8.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:5
Exact Mass:415.381415187
Heavy Atom Count:30
Complexity:643

Purity/Quality:: ≥98% by HPLC ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1CC2C(CCC(=O)N2C)(C3C1C4CCC(C4(CC3)C)C(C)CCCC(C)C)C
Isomeric SMILES:C[C@H]1C[C@@H]2[C@](CCC(=O)N2C)([C@@H]3[C@@H]1[C@@H]4CC[C@@H]([C@]4(CC3)C)[C@H](C)CCCC(C)C)C

Technology Process of 4,7beta-Dimethyl-4-azacholestan-3-one

There total 10 articles about 4,7beta-Dimethyl-4-azacholestan-3-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

: C₂₇H₄₇NO

: 74-87-3
methylene chloride

: 158493-17-5
4,7β-dimethyl-4-aza-5α-cholestan-3-one

Guidance literature:: With alumina-supported potassium hydroxide; N,N,N-trimethyl-N-butylammonium chloride; In toluene; at 20 - 65 ℃; for 2h;

Reference yield: 90.0%

: 158493-16-4
4,7β-dimethyl-4-aza-cholest-5-en-3-one

: 158493-17-5
7β-Methyl-4-methyl-4-aza-5α-cholestan-3-one

Guidance literature:: With hydrogen; Rh on carbon; In ethanol; at 30 ℃; for 24h; under 12928.7 Torr;
DOI:10.1016/0040-4039(95)01664-4

Reference yield: 87.0%

: 158493-16-4
4,7β-dimethyl-4-aza-cholest-5-en-3-one

: 158493-17-5
4,7β-dimethyl-4-aza-5β-cholestan-3-one

Guidance literature:: With 1,1'-di-tert-butyl-1-methyl silane; trifluoroacetic acid; at 25 ℃; Product distribution; Mechanism; var. temp. (60 and 100 deg C)or var. reag.:triphenylsilane, triethylsilane, hexylsilane: small β face selectivity; further reag.: TFA-d;
DOI:10.1016/0040-4039(95)01664-4