2-Methoxy-naphthalene-1-sulfinic acid [(S)-1-[2-(2-benzyloxy-ethyl)-4,5-dimethoxy-phenyl]-2-(2-cyano-4,5-dimethoxy-phenyl)-ethyl]-amide

Base Information

Chemical Name:2-Methoxy-naphthalene-1-sulfinic acid [(S)-1-[2-(2-benzyloxy-ethyl)-4,5-dimethoxy-phenyl]-2-(2-cyano-4,5-dimethoxy-phenyl)-ethyl]-amide
CAS No.:406215-72-3
Molecular Formula:C₃₉H₄₀N₂O₇S
Molecular Weight:680.822
Hs Code.:

Synonyms:2-Methoxy-naphthalene-1-sulfinic acid [(S)-1-[2-(2-benzyloxy-ethyl)-4,5-dimethoxy-phenyl]-2-(2-cyano-4,5-dimethoxy-phenyl)-ethyl]-amide

Suppliers and Price of 2-Methoxy-naphthalene-1-sulfinic acid [(S)-1-[2-(2-benzyloxy-ethyl)-4,5-dimethoxy-phenyl]-2-(2-cyano-4,5-dimethoxy-phenyl)-ethyl]-amide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 2-Methoxy-naphthalene-1-sulfinic acid [(S)-1-[2-(2-benzyloxy-ethyl)-4,5-dimethoxy-phenyl]-2-(2-cyano-4,5-dimethoxy-phenyl)-ethyl]-amide

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 2-Methoxy-naphthalene-1-sulfinic acid [(S)-1-[2-(2-benzyloxy-ethyl)-4,5-dimethoxy-phenyl]-2-(2-cyano-4,5-dimethoxy-phenyl)-ethyl]-amide

There total 8 articles about 2-Methoxy-naphthalene-1-sulfinic acid [(S)-1-[2-(2-benzyloxy-ethyl)-4,5-dimethoxy-phenyl]-2-(2-cyano-4,5-dimethoxy-phenyl)-ethyl]-amide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 68.0%

: 58814-69-0
4,5-dimethoxy-2-methyl-benzonitrile

: 2-Methoxy-naphthalene-1-sulfinic acid 1-[2-(2-benzyloxy-ethyl)-4,5-dimethoxy-phenyl]-meth-(E)-ylideneamide

: 406215-72-3
2-Methoxy-naphthalene-1-sulfinic acid [(S)-1-[2-(2-benzyloxy-ethyl)-4,5-dimethoxy-phenyl]-2-(2-cyano-4,5-dimethoxy-phenyl)-ethyl]-amide

Guidance literature:: 4,5-dimethoxy-2-methyl-benzonitrile; With lithium diisopropyl amide; In tetrahydrofuran; at -78 ℃; for 0.5h;

2-Methoxy-naphthalene-1-sulfinic acid 1-[2-(2-benzyloxy-ethyl)-4,5-dimethoxy-phenyl]-meth-(E)-ylideneamide; In tetrahydrofuran; at -78 ℃; for 0.5h; Further stages.;
DOI:10.1021/jo010988v

Reference yield:

: 494-99-5
1,2-dimethoxy-4-methylbenzene

: 406215-72-3
2-Methoxy-naphthalene-1-sulfinic acid [(S)-1-[2-(2-benzyloxy-ethyl)-4,5-dimethoxy-phenyl]-2-(2-cyano-4,5-dimethoxy-phenyl)-ethyl]-amide

Guidance literature:: Multi-step reaction with 3 steps

1.1: 85 percent / N-bromosuccinimide / CHCl₃ / 4 h / Heating

2.1: 90 percent / dimethylformamide / 16 h / 120 °C

3.1: LDA / tetrahydrofuran / 0.5 h / -78 °C

3.2: 68 percent / tetrahydrofuran / 0.5 h / -78 °C

With N-Bromosuccinimide; lithium diisopropyl amide; In tetrahydrofuran; chloroform; N,N-dimethyl-formamide;
DOI:10.1021/jo010988v

Reference yield:

: 52806-46-9
1-bromo-4,5-dimethoxy-2-methylbenzene

: 406215-72-3
2-Methoxy-naphthalene-1-sulfinic acid [(S)-1-[2-(2-benzyloxy-ethyl)-4,5-dimethoxy-phenyl]-2-(2-cyano-4,5-dimethoxy-phenyl)-ethyl]-amide

Guidance literature:: Multi-step reaction with 2 steps

1.1: 90 percent / dimethylformamide / 16 h / 120 °C

2.1: LDA / tetrahydrofuran / 0.5 h / -78 °C

2.2: 68 percent / tetrahydrofuran / 0.5 h / -78 °C

With lithium diisopropyl amide; In tetrahydrofuran; N,N-dimethyl-formamide;
DOI:10.1021/jo010988v