6-[(3R,4R,6R)-6-[2-(2-methoxy-ethoxy)-2-methyl-propyl]-4-(4-methoxy-phenyl)-1-(toluene-4-sulfonyl)-piperidin-3-yloxymethyl]-4-(3-methoxy-propyl)-3,4-dihydro-2H-benzo[1,4]oxazine

Base Information

Chemical Name:6-[(3R,4R,6R)-6-[2-(2-methoxy-ethoxy)-2-methyl-propyl]-4-(4-methoxy-phenyl)-1-(toluene-4-sulfonyl)-piperidin-3-yloxymethyl]-4-(3-methoxy-propyl)-3,4-dihydro-2H-benzo[1,4]oxazine
CAS No.:911706-20-2
Molecular Formula:C₃₉H₅₄N₂O₈S
Molecular Weight:710.932
Hs Code.:

6-[(3R,4R,6R)-6-[2-(2-methoxy-ethoxy)-2-methyl-propyl]-4-(4-methoxy-phenyl)-1-(toluene-4-sulfonyl)-piperidin-3-yloxymethyl]-4-(3-methoxy-propyl)-3,4-dihydro-2H-benzo[1,4]oxazine

Synonyms:6-[(3R,4R,6R)-6-[2-(2-methoxy-ethoxy)-2-methyl-propyl]-4-(4-methoxy-phenyl)-1-(toluene-4-sulfonyl)-piperidin-3-yloxymethyl]-4-(3-methoxy-propyl)-3,4-dihydro-2H-benzo[1,4]oxazine

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Chemical Property of 6-[(3R,4R,6R)-6-[2-(2-methoxy-ethoxy)-2-methyl-propyl]-4-(4-methoxy-phenyl)-1-(toluene-4-sulfonyl)-piperidin-3-yloxymethyl]-4-(3-methoxy-propyl)-3,4-dihydro-2H-benzo[1,4]oxazine

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Technology Process of 6-[(3R,4R,6R)-6-[2-(2-methoxy-ethoxy)-2-methyl-propyl]-4-(4-methoxy-phenyl)-1-(toluene-4-sulfonyl)-piperidin-3-yloxymethyl]-4-(3-methoxy-propyl)-3,4-dihydro-2H-benzo[1,4]oxazine

There total 1 articles about 6-[(3R,4R,6R)-6-[2-(2-methoxy-ethoxy)-2-methyl-propyl]-4-(4-methoxy-phenyl)-1-(toluene-4-sulfonyl)-piperidin-3-yloxymethyl]-4-(3-methoxy-propyl)-3,4-dihydro-2H-benzo[1,4]oxazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

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Reference yield:

: 911706-11-1
1-[(2R,4R,5R)-4-(4-methoxy-phenyl)-5-[4-(3-methoxy-propyl)-3,4-dihydro-2H-benzo[1,4]oxazin-6-ylmethoxy]-1-(toluene-4-sulfonyl)-piperidin-2-yl]-2-methyl-propan-2-ol

: 627-42-9
2-chloroethyl methyl ether

: 911706-20-2
6-[(3R,4R,6R)-6-[2-(2-methoxy-ethoxy)-2-methyl-propyl]-4-(4-methoxy-phenyl)-1-(toluene-4-sulfonyl)-piperidin-3-yloxymethyl]-4-(3-methoxy-propyl)-3,4-dihydro-2H-benzo[1,4]oxazine

Guidance literature:: 1-[(2R,4R,5R)-4-(4-methoxy-phenyl)-5-[4-(3-methoxy-propyl)-3,4-dihydro-2H-benzo[1,4]oxazin-6-ylmethoxy]-1-(toluene-4-sulfonyl)-piperidin-2-yl]-2-methyl-propan-2-ol; With sodium hydride; In tetrahydrofuran; for 0.5h;

2-chloroethyl methyl ether; With tetra-(n-butyl)ammonium iodide; In tetrahydrofuran; at 70 ℃; for 5h;