2(1H)-Quinolinone, 1-(2-(4-chlorobenzoyl)-2-propenyl)-

Base Information

Chemical Name:2(1H)-Quinolinone, 1-(2-(4-chlorobenzoyl)-2-propenyl)-
CAS No.:108664-48-8
Molecular Formula:C19H14 Cl N O2
Molecular Weight:323.779
Hs Code.:
DSSTox Substance ID:DTXSID20148695
Wikidata:Q83014290
ChEMBL ID:CHEMBL35120
Mol file:108664-48-8.mol

Synonyms:108664-48-8;2(1H)-Quinolinone, 1-(2-(4-chlorobenzoyl)-2-propenyl)-;1-[2-(4-CHLOROBENZOYL)-2-PROPENYL]-2(1H)-QUINOLINONE;2(1H)-Quinolinone, 1-[2-(4-chlorobenzoyl)-2-propenyl]-;CHEMBL35120;DTXSID20148695;1-[2-(4-chlorobenzoyl)allyl]quinolin-2-one

Suppliers and Price of 2(1H)-Quinolinone, 1-(2-(4-chlorobenzoyl)-2-propenyl)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of 2(1H)-Quinolinone, 1-(2-(4-chlorobenzoyl)-2-propenyl)-

Chemical Property:

Vapor Pressure:1.51E-09mmHg at 25°C
Boiling Point:484.6°Cat760mmHg
Flash Point:246.9°C
Density:1.274g/cm³
XLogP3:3.9
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:4
Exact Mass:323.0713064
Heavy Atom Count:23
Complexity:520

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C=C(CN1C(=O)C=CC2=CC=CC=C21)C(=O)C3=CC=C(C=C3)Cl

Technology Process of 2(1H)-Quinolinone, 1-(2-(4-chlorobenzoyl)-2-propenyl)-

There total 2 articles about 2(1H)-Quinolinone, 1-(2-(4-chlorobenzoyl)-2-propenyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 56.0%

: 51-80-9
bis-(dimethylamino)methane

: 108664-82-0
1-[3-(4-Chloro-phenyl)-3-oxo-propyl]-1H-quinolin-2-one

: 108664-48-8
1-[2-(4-Chloro-benzoyl)-allyl]-1H-quinolin-2-one

Guidance literature:: With acetic anhydride; at 80 ℃; for 1h;
DOI:10.1021/jm00391a037

Reference yield:

: 33994-12-6
3-bromo-1-(4-chlorophenyl)propan-1-one

: 108664-48-8
1-[2-(4-Chloro-benzoyl)-allyl]-1H-quinolin-2-one

Guidance literature:: Multi-step reaction with 2 steps

1: 650 mg / NaH / dimethylformamide / 0.25 h / Ambient temperature

2: 56 percent / Ac₂O / 1 h / 80 °C

With acetic anhydride; sodium hydride; In N,N-dimethyl-formamide;
DOI:10.1021/jm00391a037