4-(4-Amino-3-nitro-phenyl)-2,6-dimethyl-1,4-dihydro-pyridine-3,5-dicarboxylic acid dimethyl ester

Base Information

Chemical Name:4-(4-Amino-3-nitro-phenyl)-2,6-dimethyl-1,4-dihydro-pyridine-3,5-dicarboxylic acid dimethyl ester
CAS No.:121497-08-3
Molecular Formula:C₁₇H₁₉N₃O₆
Molecular Weight:361.354
Hs Code.:

Synonyms:4-(4-Amino-3-nitro-phenyl)-2,6-dimethyl-1,4-dihydro-pyridine-3,5-dicarboxylic acid dimethyl ester

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Chemical Property of 4-(4-Amino-3-nitro-phenyl)-2,6-dimethyl-1,4-dihydro-pyridine-3,5-dicarboxylic acid dimethyl ester

Chemical Property:

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MSDS Files:: SDS file from LookChem

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Technology Process of 4-(4-Amino-3-nitro-phenyl)-2,6-dimethyl-1,4-dihydro-pyridine-3,5-dicarboxylic acid dimethyl ester

There total 1 articles about 4-(4-Amino-3-nitro-phenyl)-2,6-dimethyl-1,4-dihydro-pyridine-3,5-dicarboxylic acid dimethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 68.0%

: 51818-99-6
4-amino-3-nitro-benzaldehyde

: 14205-39-1
methyl 3-aminocrotonate

: 121497-08-3
4-(4-Amino-3-nitro-phenyl)-2,6-dimethyl-1,4-dihydro-pyridine-3,5-dicarboxylic acid dimethyl ester

Guidance literature:: In ethylene glycol; for 24h; Heating;
DOI:10.1021/jm00130a012

Reference yield: 72.0%

: 121497-08-3
4-(4-Amino-3-nitro-phenyl)-2,6-dimethyl-1,4-dihydro-pyridine-3,5-dicarboxylic acid dimethyl ester

: 121497-15-2
4-(3,4-diaminophenyl)-2,6-dimethyl-3,5-bis(methoxycarbonyl)-1,4-dihydropyridine

Guidance literature:: With hydrogen; nickel; In methanol; for 2h; under 1838.8 Torr;
DOI:10.1021/jm00130a012

Reference yield:

: 121497-08-3
4-(4-Amino-3-nitro-phenyl)-2,6-dimethyl-1,4-dihydro-pyridine-3,5-dicarboxylic acid dimethyl ester

: 121497-21-0
4-[3-(4-Methoxy-benzyl)-2-(4-methoxy-phenyl)-3H-benzoimidazol-5-yl]-2,6-dimethyl-1,4-dihydro-pyridine-3,5-dicarboxylic acid dimethyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 72 percent / H₂ / Raney Ni / methanol / 2 h / 1838.8 Torr

2: 66 percent / acetic acid / 4 h / water bath

With hydrogen; nickel; In methanol; acetic acid;
DOI:10.1021/jm00130a012